化工新型材料

化工新型材料 ›› 2018, Vol. 46 ›› Issue (7) : 131-134.

新材料与新技术

新型噻唑衍生物的合成及对Fe³⁺的识别

刘天宝, 彭艳芬, 桂美芳

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Synthesis of a novel thiazole derivative and its selective detection of Fe³⁺

Liu Tianbao, Peng Yanfen, Gui Meifang

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Received		Published
2017-03-29		2018-07-20
Issue Date	Revised Date
2018-08-07	2017-03-29

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摘要

以3-邻氯苯甲酰基-1-苯基硫脲和2-溴代苯乙酮为原料,设计合成了一种新型的噻唑衍生物2-邻氯苯甲酰亚氨基-3,4-二苯基-1,3-噻唑(CDT),并采用傅里叶变换红外光谱、核磁共振氢谱、核磁共振碳谱对其结构进行了表征。结果表明:化合物CDT可作为荧光探针选择性识别Fe³⁺,且几乎不受其他常见金属离子(Ag⁺,Al³⁺,Ba²⁺,Ca²⁺,Cd²⁺,Co²⁺,Cu²⁺,Hg²⁺,K⁺,Mg²⁺,Na⁺,Pb²⁺,Zn²⁺)的干扰。探针CDT的荧光强度与Fe³⁺的浓度(2×10^-6～6×10^-5mol/L)呈良好的线性关系,复相关系数R²为0.9965。CDT对Fe³⁺检出限为9.7×10^-7mol/L,二者络合常数为3.3×10⁴L/mol,络合比为1∶1。

Abstract

A new thiazole derivative,2-o-chlorobenzoylimino-3,4-diphenyl-1,3-thiazole (CDT),was prepared from 3-o-Chlorobenzoyl-1-phenylthiourea with 2-bromoacetophenone,and its structure was confirmed by FT-IR,¹H-NMR and ¹³C-NMR.The results showed that the compound CDT exhibited the selective to Fe³⁺,and other metal ions (Ag⁺,Al³⁺,Ba²⁺,Ca²⁺,Cd²⁺,Co²⁺,Cu²⁺,Hg²⁺,K⁺,Mg²⁺,Na⁺,Pb²⁺,Zn²⁺) did not interfere with its recognition.A linear relationship was observed between the fluorescence intensity of probe CDT and the concentration of Fe³⁺ in the range of 2×10^-6～6×10^-5mol/L (R²=0.9965).The detection limit of CDT for Fe³⁺ was 9.7×10^-7mol/L.The complex constant between CDT and Fe³⁺ was 3.3×10⁴L/mol.Meanwhile,the binding ratio of CDT and Fe³⁺ was found to be 1∶1.

关键词

噻唑 / 铁离子 / 荧光探针 / 识别

Key words

thiazole / iron(Ⅲ) ion / fluorescent probe / recognition

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