电化学传感器在可穿戴健康监测领域的应用进展

李倩, 贾涵丽, 张洋, 杨群, 薄敬东, 赵鑫, 崔传金

化工新型材料 ›› 2026, Vol. 54 ›› Issue (10) : 1 -6.

PDF
化工新型材料 ›› 2026, Vol. 54 ›› Issue (10) : 1-6. DOI: 10.19817/j.cnki.issn1006-3536.2026.10.020
柔性电子材料创新与应用专题

电化学传感器在可穿戴健康监测领域的应用进展

    李倩, 贾涵丽, 张洋, 杨群, 薄敬东, 赵鑫, 崔传金
作者信息 +

Application progress of electrochemical sensors in wearable health monitoring

  • Li Qian, Jia Hanli, Zhang Yang, Yang Qun, Bo Jingdong, Zhao Xin, Cui Chuanjin
Author information +
文章历史 +
PDF

摘要

随着可穿戴技术与健康管理需求的深度融合,电化学传感器凭借高灵敏度、快速响应的核心优势,在可穿戴健康监测领域的应用价值愈发突出。系统阐述了电化学传感器的基本概念、工作原理及主要类型,分析其在材料特性与技术性能上的优势。重点综述其在可穿戴健康监测中的实际应用,包括多生物标志物实时监测、血压监测、心理健康监测及心血管健康监测等。同时指出当前面临长期稳定性不足、信号干扰及临床转化标准化缺失等挑战,以期为电化学传感器领域研究锚定技术突破方向与应用落地路径,赋于可穿戴电化学传感器向健康监测实用化、精准化发展。

Abstract

with the deep integration of wearable technology and health management needs,electrochemical sensors have become increasingly prominent in the field of wearable health monitoring due to their core advantages of high sensitivity and fast response.In this paper,the basic concept,working principle and main types of electrochemical sensors were systematically described,and their advantages in material properties and technical performance were analyzed.This paper focused on their practical applications in wearable health monitoring,including real-time monitoring of multi-biomarkers,blood pressure monitoring,mental health monitoring and cardiovascular health monitoring.At the same time,it was pointed out that the current challenges were insufficient long-term stability,signal interference and lack of standardization in clinical translation.This review provides a breakthrough direction and application path for anchoring technology research in the field of electrochemical sensors,enabling wearable electrochemical sensors to be practical and accurate for health monitoring.

关键词

电化学传感器 / 可穿戴设备 / 健康监测

Key words

electrochemical sensors / wearable devices / health monitoring

引用本文

引用格式 ▾
电化学传感器在可穿戴健康监测领域的应用进展[J]. 化工新型材料, 2026, 54(10): 1-6 DOI:10.19817/j.cnki.issn1006-3536.2026.10.020

登录浏览全文

4963

注册一个新账户 忘记密码

参考文献

[1] Ferrara E.Large language models for wearable sensor-based human activity recognition,health monitoring,and behavioral modeling:a survey of early trends,datasets,and challenges[J].Sensors,2024,24(15):5045.
[2] Zang J,An Q,Li B,et al.A novel wearable device integrating ECG and PCG for cardiac health monitoring[J].Microsystems & Nanoengineering,2025,11(1):7.
[3] Taylor L,Ding X,Clifton D,et al.Wearable vital signs monitoring for patients with asthma:a review[J].IEEE Sensors Journal,2020,23(3):1734-1751.
[4] Yu Z,Luo T,Lu J,et al.Wireless wearable multifunctional sensor based on carboxylated cellulose nanofibers/silver nanowires for ultra-sensitive,fast humidity response and body temperature monitoring[J].International Journal of Biological Macromolecules,2025,290:138934.
[5] Anik Ü,Tepeli Y,Diouani M F.Fabrication of electrochemical model influenza a virus biosensor based on the measurements of neuroaminidase enzyme activity[J].Analytical Chemistry,2016,88(12):6151-6153.
[6] Lee H,Reginald S S,Sravan J S,et al.Advanced strategies for enzyme-electrode interfacing in bioelectrocatalytic systems[J].Trends in Biotechnology,2025,43(6):1328-1355.
[7] He Y,Luo L,Li L,et al.Synergistic signal-amplification effect of silver nanowires and bifunctional monomers on molecularly imprinted electrochemical sensor for diuron analysis[J].Biosensors and Bioelectronics,2024,262:116570.
[8] Lu M,Shen L,Su H,et al.Highly ionic conductive,elastic,and biocompatible double-network composite gel for epidermal biopotential monitoring and wearable sensing[J].Journal of Colloid and Interface Science,2025,684:272-282.
[9] Lv R,Cao X,Zhang T,et al.A highly stretchable,self-healing,self-adhesive polyacrylic acid/chitosan multifunctional composite hydrogel for flexible strain sensors[J].Carbohydrate Polymers,2025,351:123111.
[10] Wang J,Zhao K,Zhao Y,et al.Highly conductive,ultratough,and adhesive eutectogels with environmental tolerance enabled by liquid metal composites[J].Small,2025,21(9):2410806.
[11] Huang W,Yang Y,Xu Y,et al.Sweat wearable sensor based on confined pt nanoparticles in 2d conductive metal-organic frameworks for continuous glucose monitoring[J].Advanced Science,2025,12(35):e202507212.
[12] Chen Y,He Z,Wu Y,et al.A Wearable molecularly imprinted electrochemical sensor for cortisol stable monitoring in sweat[J].Biosensors,2025,15(3):194.
[13] Lv M,Qiao X,Li Y,et al.A stretchable wearable sensor with dual working electrodes for reliable detection of uric acid in sweat[J].Analytica Chimica Acta,2024,1287:342154.
[14] Gao W,Xu H,Sun X,et al.An integrated wearable photoelectrochemical sensor for visible light amplified uric acid monitoring in sweat[J].Biosensors and Bioelectronics,2025,289(1):117892.
[15] Lv M,Wang L,Hou Y,et al.A wearable antifouling electrochemical sensor integrated with an antimicrobial microneedle array for uric acid detection in interstitial fluid[J].Analytica Chimica Acta,2025,1339:343610.
[16] Yang M,Wang H,Cheng J,et al.Continuous monitoring of multiple biomarkers with an ultrasensitive 3D-structured wearable biosensor[J].Cell Reports Methods,2023,3(9):100579.
[17] Wang C,Zhang Y,Liu Y,et al.A wearable flexible electrochemical biosensor with CuNi-MOF@rGO modification for simultaneous detection of uric acid and dopamine in sweat[J].Analytica Chimica Acta,2024,1299:342441.
[18] Noor A M,Al Farisi M S,Mazalan M,et al.Wearable device for continuous and real-time monitoring of human sweat sodium[J].Sensors,2025,25(11):3467.
[19] Xuan X,Chen C,Molinero-Fernandez A,et al.Fully integrated wearable device for continuous sweat lactate monitoring in sports[J].ACS Sensors,2023,8(6):2401-2409.
[20] Ma L,Hou W,Ji Z,et al.Wearable electrochemical sensor for sweat-based potassium ion and glucose detection in exercise health monitoring[J].Chemistry Open,2024,13(8):e202300217.
[21] Arcangeli D,Gualandi I,Mariani F,et al.Smart bandaid integrated with fully textile OECT for uric acid real-time monitoring in wound exudate[J].ACS Sensors,2023,8(4):1593-1608.
[22] Chen Y,Zhang X,Liu Y,et al.A Gold Nanoparticles and Mxene nanocomposite based electrochemical sensor for point-of-care monitoring of serum biomarkers[J].ACS Nano,2025,19(17):16980-16994.
[23] Garg M,Guo H,Maclam E,et al.Molecularly imprinted wearable sensor with paper microfluidics for real-time sweat biomarker analysis[J].ACS Applied Materials & Interfaces,2024,16(35):46113-46122.
[24] Bhide A,Cheeran S,Muthukumar S,et al.Enzymatic low volume passive sweat based assays for multi-biomarker detection[J].Biosensors (Basel),2019,9(1):13.
[25] Duan H,Peng S,He S,et al.Wearable electrochemical biosensors for advanced healthcare monitoring[J].Advanced Science,2025,12(2):2411433.
[26] Mannoor M S,Tao H,Clayton J D,et al.Graphene-based wireless bacteria detection on tooth enamel[J].Nature Communications,2012,3(3):763.
[27] Arakawa T,Tomoto K,Nitta H,et al.A Wearable cellulose acetate-coated mouthguard biosensor for in vivo salivary glucose measurement[J].Analytical Chemistry,2020,92(18):12201-12207.
[28] Chen F,Wang J,Chen L,et al.A wearable electrochemical biosensor utilizing functionalized Ti3C2Tx mxene for the real-time monitoring of uric acid metabolite[J].Analytical Chemistry,2024,96(9):3914-3924.
[29] Singh A,Ahmed A,Sharma A,et al.Graphene and its derivatives:synthesis and application in the electrochemical detection of analytes in sweat[J].Biosensors,2022,12(10):910.
[30] Phan D T,Nguyen C H,Nguyen T D P,et al.A flexible,wearable,and wireless biosensor patch with internet of medical things applications[J].Biosensors,2022,12(3):139.
[31] McMurray J P,DeVries A,Frazee K,et al.A novel wearable device for continuous blood pressure monitoring utilizing strain gauge technology[J].Biosensors,2025,15(7):413.
[32] McGillion M H,Dvirnik N,Yang S,et al.Continuous noninvasive remote automated blood pressure monitoring with novel wearable technology:a preliminary validation study[J].JMIR mHealth and uHealth,2022,10(2):e24916.
[33] Rachim V P,Chung W Y.Multimodal wrist biosensor for wearable cuff-less blood pressure monitoring system[J].Scientific Reports,2019,9(1):7947.
[34] Hillmann H A K,Soltani S,Mueller-Leisse J,et al.Cardiac rhythm monitoring using wearables for clinical guidance before and after catheter ablation[J].Journal of Clinical Medicine,2022,11(9):2428.
[35] Dulay S,Rivas L,Pla L,et al.Fetal ischemia monitoring with in vivo implanted electrochemical multiparametric microsensors[J].Journal of Biological Engineering,2021,15(1):28.
[36] Ahmed N,Zhu Y.Early detection of atrial fibrillation based on ECG signals[J].Bioengineering,2020,7(1):16.
[37] Kumar S,Kedia R,Bisht A,et al.Novel flexible organic photoplethysmogram sensor for continuous cardiovascular monitoring[J].ACS Sensors,2025,10(6):4297-4306.
[38] Zhang Z,Wei W,Li A,et al.High accuracy sensor for two-parameter detection of adrenaline and pH in sweat[J].Biosensors and Bioelectronics,2025,287:117675.
[39] Saha T,Songkakul T,Knisely C T,et al.Wireless wearable electrochemical sensing platform with zero-power osmotic sweat extraction for continuous lactate monitoring[J].ACS Sensors,2022,7(7):2307-2316.
[40] Mohammed N,Cluff K,Sutton M,et al.A flexible near-field biosensor for multisite arterial blood flow detection[J].Sensors,2022,22(21):8389.
[41] Kargarandehkordi A,Li S,Lin K,et al.Fusing wearable biosensors with artificial intelligence for mental health monitoring:a systematic review[J].Biosensors,2025,15(4):202.
[42] Wang C,He A,Han G,et al.An ultrastable wearable electrochemical sensor for prolonged monitoring of electrolyte loss and hydration[J].ACS Sensors,2025,10(7):4954-4962.

基金资助

2024年度华北理工大学重大科研项目(ZD-YG-202421);2025年度河北省医学科学研究课题计划(20251018)

AI Summary AI Mindmap
PDF

87

访问

0

被引

导航
相关文章

AI思维导图

/

〈 〉