静电纺智能纳米纤维在健康监测领域的应用进展

李莹, 姜宇昊, 王岩, 魏梦丹

化工新型材料 ›› 2026, Vol. 54 ›› Issue (6) : 15 -20.

PDF (1148KB)
化工新型材料 ›› 2026, Vol. 54 ›› Issue (6) : 15-20. DOI: 10.19817/j.cnki.issn1006-3536.2026.06.018
综述与专论

静电纺智能纳米纤维在健康监测领域的应用进展

    李莹, 姜宇昊, 王岩, 魏梦丹
作者信息 +

Application progress of electrospun intelligent nanofibers in health monitoring

  • Li Ying, Jiang Yuhao, Wang Yan, Wei Mengdan
Author information +
文章历史 +
PDF (1175K)

摘要

近年来,人口老龄化、慢性病管理的增长趋势促进了人体健康监测技术及产品的需求。尽管人们对生物传感器进行了大量研究,但柔性、寿命与稳定性仍是当前生物传感器发展的主要难题。基于静电纺丝纳米纤维材料特点及其在人体健康监测中的重要作用,综述了静电纺智能纳米纤维在人体活动监测、生物标志物监测及药物缓释方面的应用进展,并展望了未来功能性纳米纤维生物传感材料的研究方向。

Abstract

In recent years,the growth trends of aging population and chronic disease management have promoted the demand for human health monitoring technologies and products.Although extensive research has been conducted on biosensors,flexibility,lifespan and stability remain the main challenges in the current development of biosensors.Based on the characteristics of electrospun nanofiber materials and their significant role in human health monitoring,this paper reviewed the application progress of electrospun intelligent nanofibers in human activity monitoring,biomarker monitoring and drug sustained-release,and looked forward to the future research directions of functional nanofiber biosensing materials.

关键词

静电纺丝 / 纳米纤维 / 智能可穿戴 / 生物传感器

Key words

electrospinning / nanofibers / intelligent wearable / biosensor

引用本文

引用格式 ▾
静电纺智能纳米纤维在健康监测领域的应用进展[J]. 化工新型材料, 2026, 54(6): 15-20 DOI:10.19817/j.cnki.issn1006-3536.2026.06.018

登录浏览全文

4963

注册一个新账户 忘记密码

参考文献

[1] Chen S,Fan S,Qiao Z,et al.Transforming healthcare:intelligent wearable sensors empowered by smart materials and artificial intelligence[J].Adv Mater,2025,37(21):2500412.
[2] Kailasa S,Reddy M S B,Maurya M R,et al.Electrospun nanofibers:materials,synthesis parameters,and their role in sen-sing applications[J].Macromolecular Materials and Engineering,2021,306(11):2100410.
[3] Ji G,Chen Z,Li H,et al.Electrospinning-based biosensors for health monitoring[J].Biosensors,2022,12(10):876.
[4] Zhang Z,Jia S,Wu W,et al.Electrospun transparent nanofibers as a next generation face filtration media:a review[J].Biomaterials Advances,2023,149:213390.
[5] Halim N,Nallusamy N,Lakshminarayanan R,et al.Electrospinning in drug delivery:progress and future outlook[J].Macromol Rapid Commun,2025,46(13):2400903.
[6] Zhang J H,Sun X,Wang H,et al.From 1D to 2D to 3D:electrospun microstructures towards wearable sensing[J].Che-mosensors,2023,11(5):295.
[7] Wang S,Fan P,Liu W,et al.Research progress of flexible electronic devices based on electrospun nanofibers[J].ACS Nano,2024,18(46):31737-31772.
[8] Wang X,Feng Z,Zhang G,et al.Flexible sensors array based on frosted microstructured ecoflex film and TPU nanofibers for epidermal pulse wave monitoring[J].Sensors,2023,23(7):3717.
[9] Li W,Lin J,Chu W,et al.Polyimide composite fiber containing fluorine for respiratory monitoring and wearable electronics[J].Polymer,2025,328:128479.
[10] Phadkule S S,Sarma S.High-performance flexible temperature sensor from hybrid nanocomposite for continuous human body temperature monitoring[J].Polymer Composites,2023,44(2):1381-1391.
[11] Zhang J,Wang Z,Huang Y,et al.Flexible piezoelectric sensor based on polyacrylonitrile/MWCNT/MXene composites films for human physiological health detection[J].Journal of Applied Polymer Science,2024,141(9):55009.
[12] Li X,Chen S,Zhang X,et al.Poly-L-lactic acid/graphene electrospun composite nanofibers for wearable sensors[J].Energy Technology,2020,8(5):1901252.
[13] Lou M,Abdalla I,Zhu M,et al.Hierarchically rough structured and self-powered pressure sensor textile for motion sensing and pulse monitoring[J].ACS Applied Materials & Interfaces,2020,12(1):1597-1605.
[14] Wang R,Yu Y,Zuo Y,et al.Airflow-induced flexoelectric bending sensors for human breath detection[J].IEEE Sensors Journal,2024,24(5):5950-5958.
[15] Lee H,Jeon S.Polyacrylonitrile nanofiber membranes modified with Ni-based conductive metal organic frameworks for air filtration and respiration monitoring[J].ACS Applied Nano Materials,2020,3(8):8192-8198.
[16] Zhang J,Wang X X,Zhang B,et al.In situ assembly of well-dispersed Ag nanoparticles throughout electrospun alginate nanofibers for monitoring human breath—smart fabrics[J].ACS Applied Materials & Interfaces,2018,10(23):19863-19870.
[17] Li X,Zhuang Z,Qi D,et al.High sensitive and fast response humidity sensor based on polymer composite nanofibers for breath monitoring and non-contact sensing[J].Sensors and Actuators B:Chemical,2021,330:129239.
[18] Wang S,Yan X,Zhang T,et al.All-nanofiber iontronic sensor with multiple sensory capabilities for wearable electronics[J].Advanced Materials Technologies,2024,9(9):2301791.
[19] Ding S,Jin X,Guo J,et al.A biomimetic asymmetric structured intelligent wound dressing with dual-modality humidity-pressure sensing for non-invasive and real-time wound healing monitoring[J].Advanced Fiber Materials,2025,7(1):156-171.
[20] Guk K,Han G,Lim J,et al.Evolution of wearable devices with real-time disease monitoring for personalized healthcare[J].Nanomaterials,2019,9(6):813.
[21] Ramesh Gawali C,Daweshar E,Kolhe A,et al.Recent advances in nanostructured conducting polymer electrospun for application in electrochemical biosensors[J].Microchemical Journal,2024,200:110326.
[22] Wei L,Li Z,Dai Z,et al.Wearable sweat management techno-logies[J].Advanced Materials Technologies,2024,9(7):2301812.
[23] Liu Y L,Liu R,Qin Y,et al.Flexible electrochemical urea sensor based on surface molecularly imprinted nanotubes for detection of human sweat[J].Analytical Chemistry,2018,90(21):13081-13087.
[24] Liu X,Jiang B,Feng Y,et al.Hierarchically engineering of bioinspired sweat-resistant interlock-structured piezoelectric sensor for self-powered physical rehabilitation and healthcare[J].Chemical Engineering Journal,2025,512:162534.
[25] Ali S,Abdalla I,Chen G,et al.Non-invasive wearable nanoporous device for real-time monitoring of glucose in sweat[J].Composites Part B:Engineering,2025,303:112613.
[26] Liang X,Meng S,Zhi C,et al.Thermal transfer printed flexible and wearable bionic skin with bilayer nanofiber for comfortable multimodal health management[J].Advanced Healthcare Materials,2025,14(6):2403780.
[27] Yu W,Li Q,Ren J,et al.A sensor platform based on SERS detection/janus textile for sweat glucose and lactate analysis toward portable monitoring of wellness status[J].Biosensors and Bioelectronics,2024,263:116612.
[28] Niu Q,Yuan R,Zhan H,et al.Janus membrane-based wearable dual-channel SERS sensor for sweat collection and monitoring of lactic acid and pH levels[J].Analytical Chemistry,2025,97(11):6083-6091.
[29] Jin L,Zheng Y,Liu Z,et al.Design of an ultrasensitive flexible bend sensor using a silver-doped oriented poly(vinylidene fluoride) nanofiber web for respiratory monitoring[J].ACS Applied Materials & Interfaces,2020,12(1):1359-1367.
[30] Chang Y H,Hsieh T H,Hsiao K C,et al.Electrospun fibrous nanocomposite sensing materials for monitoring biomarkers in exhaled Breath[J].Polymers,2023,15(8):1833.
[31] Chen X,Liang R,Qin C,et al.Coaxial electrospinning Fe2O3@Co3O4 double-shelled nanotubes for enhanced ethanol sen-sing performance in a wide humidity range[J].Journal of Alloys and Compounds,2022,891:161868.
[32] Mohamadbeigi N,Shooshtari L,Fardindoost S,et al.Self-powered triboelectric nanogenerator sensor for detecting humidity level and monitoring ethanol variation in a simulated exhalation environment[J].Scientific Reports,2024,14(1):1562.
[33] Farzin L,Sadjadi S,Shamsipur M,et al.Employing AgNPs doped amidoxime-modified polyacrylonitrile (PAN-oxime) nanofibers for target induced strand displacement-based electrochemical aptasensing of CA125 in ovarian cancer patients[J].Materials Science and Engineering:C,2019,97:679-687.
[34] An J E,Kim K H,Park S J,et al.Wearable cortisol aptasensor for simple and rapid real-time monitoring[J].ACS Sensors,2022,7(1):99-108.
[35] Sunil N,Unnathpadi R,Pullithadathil B.Label-free SERS salivary biosensor based on Ni@Ag core-shell nanoparticles anchored on carbon nanofibers for prediagnosis of lung cancer[J].ACS Applied Nano Materials,2023,6(13):11334-11350.
[36] Yang G,Li X,He Y,et al.Capturing circulating tumor cells through a combination of hierarchical nanotopography and surface chemistry[J].ACS Biomaterials Science & Engineering,2018,4(6):2081-2088.
[37] Chen M,Li Y F,Besenbacher F.Electrospun nanofibers-mediated on-demand drug release[J].Advanced Healthcare Materials,2014,3(11):1721-1732.
[38] Schoeller J,Fabian I,Karin W K,et al.pH-responsive electrospun nanofibers and their applications[J].Polymer Reviews,2022,62(2):351-399.
[39] Tiwari A P,Hwang T I,Oh J M,et al.pH/NIR-responsive polypyrrole-functionalized fibrous localized drug-delivery platform for synergistic cancer therapy[J].ACS Appl Mater Interfaces,2018,10(24):20256-20270.
[40] Li Y,He C,Tang Y,et al.Novel thermal-regulation and temperature-responsive controlled-release fibermats with porous sheath-core structures[J].Polymer,2024,313:127713.
[41] Yan B Y,Cao Z K,Hui C,et al.MXene@hydrogel composite nanofibers with the photo-stimulus response and optical monitoring functions for on-demand drug release[J].Journal of Colloid and Interface Science,2023,648:963-971.
[42] Croitoru A M,Karaçelebi Y,Saatcioglu E,et al.Electrically triggered drug delivery from novel electrospun poly(lactic acid)/graphene oxide/quercetin fibrous scaffolds for wound dressing applications[J].Pharmaceutics,2021,13(7):957.

基金资助

陕西省重点研发计划项目(2025CYYBXM241)

AI Summary AI Mindmap
PDF (1148KB)

71

访问

0

被引

导航
相关文章

AI思维导图

/