通过同轴静电纺丝技术制备了具有明确芯-壳结构的聚己内酯(PCL)/聚乳酸(PLA)复合纤维膜。采用场发射扫描电子显微镜和透射电子显微镜研究了芯层与壳层纺丝液浓度、总流速以及芯壳流速比等关键参数对纤维形貌和内部结构的调控规律。结合电子万能试验机、接触角测量仪测试了复合纤维膜的力学性能和表面润湿性,采用傅里叶变换红外光谱仪表征了复合纤维膜的化学组成特征。结果表明:提高纺丝液浓度和总流速,可以有效增加纤维平均直径;当芯壳流速比从1∶3降至1∶5时,内芯直径占比逐渐减小,同轴结构特征更为显著。
Polycaprolactone (PCL)/polylactic acid (PLA) composite fiber membranes with well-defined core-shell structures were prepared using coaxial electrospinning technology.Field emission scanning electron microscopy (FE-SEM) and transmission electron microscopy (TEM) were used to investigate the effects of key parameters,such as the concentrations of core and shell solutions,total flow rate,and core-shell flow rate ratio,on the fiber morphology and internal structure.The mechanical properties and surface wettability of the composite fiber membrane were measured using a universal testing machine and a contact angle goniometer,while the chemical composition characteristics were analyzed using Fourier transform infrared spectroscopy (FT-IR).The results showed that increasing the solution concentration and the total flow rate effectively increased the average fiber diameter.When the core-shell flow rate ratio decreased from 1∶3 to 1∶5,the proportion of the inner core diameter gradually decreased,making the coaxial structure more pronounced.
[1] Xu X,Ren S,Li L,et al.Biodegradable engineered fiber scaffolds fabricated by electrospinning for periodontal tissue regeneration[J].Biomater Appl,2021,36(1):55-75.
[2] 张海悦,韩峰,陈浩.电纺纳米纤维材料在生物医学领域研究进展[J].化工新型材料,2024,52(S1):58-64.
[3] Yu H,Chen D,Lu W,et al.Characterization of polyvinyl alcohol/chitosan nanofibers loaded with royal jelly by blending electrospinning for potential wound dressings[J].International Journal of Biological Macromolecules,2025,307:141977.
[4] 郭琛琰,张怀平,李伟.同轴静电纺丝法制备气体传感器的研究进展[J].化工新型材料,2024,52(11):52-56.
[5] Soltanabadi H,Rafiee E,Ghaderi R.Cobalt-polyoxometalate-PVDF nanofibers a flexible,self-powered and high-sensitive piezoelectric sensor[J].Colloids and Surfaces A:Physicoche-mical and Engineering Aspects,2025,712:136442.
[6] 考鸿铭,李龙云,许功豪,等.具有稳定超疏水性能的高效油水分离膜的制备及性能研究[J].化工新型材料,2025,53(12):1-10.
[7] 尹勃涵,贾宏葛.静电纺ODA-ODPA/SDS纳米纤维膜的制备及其乳液分离性能研究[J].化工新型材料,2025,53(7):203-206.
[8] 王改改,刘让同,徐薇仪,等.核壳结构多孔纳米纤维膜的制备及油水分离性能研究[J].化工新型材料,2024,52(5):133-140.
[9] 许云飞,苏杨帆,卢杭诣,等.同轴静电纺丝法制备纤维素基复合纳米纤维及其性能研究[J].化工新型材料,2015,43(4):55-57;60.
[10] Abodunrin D O,Bricha M,Mabrouk E K.Evaluating the bioactive capability and analysis of amoxicillin release mechanisms in PCL/PVP nanofibers using bioactive glass as a drug carrier[J].Biomedical Materials & Devices,2025,4(1):1-23.
[11] Sharma A,Alam A M,Dhoundiyal S.Fiber technology in drug delivery and pharmaceuticals[J].Current Drug Delivery,2025,22(3):261-282.
[12] Zhang Z,Liu H,Yu G D,et al.Alginate-based electrospun nanofibers and the enabled drug controlled release profiles:a review[J].Biomolecules,2024,14(7):789.
[13] Abdollahi S,Chamchangi A M,Raoufi Z,et al.Dual-layer alginate hydrogel dressings with chitosan nanofibers for enhanced wound healing,infection prevention,and controlled drug release[J].International Journal of Biological Macromolecules,2025,307:142033.
[14] Khodabandeh A,Yousefi A A,Holagh J S,et al.Fabrication of 3D microfibrous composite polycaprolactone/hydroxyapatite scaffolds loaded with piezoelectric poly (lactic acid) nanofibers by sequential near-field and conventional electrospinning for bone tissue engineering[J].Biomaterials Advances,2025,166:214053.
[15] Havlíková T,Papež N,Fohlerová Z,et al.Adaptability of electrospun PVDF nanofibers in bone tissue engineering[J].Polymers,2025,17(3):330.
[16] Gunatillake P A,Adhikari R.Biodegradable synthetic polymers for tissue engineering[J].European Cells and Materials,2003,5(1):1-16.
[17] 朱染染,唐永涛,王增坤,等.静电纺PLA/PCL复合纳米纤维膜的制备及性能研究[J].化工新型材料,2023,51(4):137-141.
[18] 唐梦瑶,麻文效,张晴.DK/PVA复合膜的制备及药物缓释性能研究[J].化工新型材料,2025,53(S1):328-333.
[19] 廉通,师云龙,钱晓明,等.基于交联技术改性聚己内酯静电纺丝织物的研究进展[J].化工新型材料,2023,51(10):49-53;59.
[20] 刘焕朝,孙奇浩,张雪,等.星型聚己内酯对聚乳酸性能的影响[J].工程塑料应用,2018,46(12):13-17.
基金资助
国家自然科学基金-地区科学基金项目(52365053)
PDF
(1248KB)
