抗菌材料对防止感染传播、预防疾病传播、减少抗生素耐药性及保障医疗环境安全具有重要意义,抗菌材料也是维护公共健康、环境清洁、保护医疗和食品行业安全的重要支持,但目前抗菌材料面临环境适应性、细菌抗性、成本及抗菌效果可持续性等挑战。因此,需要不断研发新型抗菌材料以应对挑战。稀土复合抗菌材料比传统抗菌剂具有高效广谱、长效稳定、安全环保的显著优势。综述了稀土抗菌材料的研究进展及其发展趋势,对稀土抗菌材料的抗菌机理进行了归纳和总结,最后介绍了稀土抗菌材料在医疗卫生、食品加工、环保等方面的应用。
Antibacterial materials are essential for preventing infections,curbing disease transmission,mitigating antibiotic resistance,and ensuring the safety of medical environments.They also play a critical role in promoting public health,maintaining environmental cleanliness,and safeguarding the medical and food industries.However,existing antibacterial materials face challenges such as environmental adaptability,bacterial resistance,cost,and the sustainability of antibacterial efficacy.This underscores the need for ongoing innovation in the development of advanced antibacterial materials.Rare earth composite antibacterial materials stand out with distinct advantages over conventional agents,including high efficiency,broad-spectrum activity,long-lasting performance,safety,and environmental friendliness.This review provided a comprehensive overview of the research progress and emerging trends in rare earth antibacterial materials,discussed their antibacterial mechanisms,and highlighted their applications in healthcare,food processing,and environmental protection.
[1] 汪子翔,张坤,卫金皓,等.抗菌材料及抗菌剂的研究现状及前景展望[J].橡塑技术与装备,2021,47(12):22-29.
[2] Bassous N J,Garcia C B,Webster T J.A study of the chemistries,growth mechanisms,and antibacterial properties of cerium- and yttrium-containing nanoparticles[J].ACS Biomaterials Science & Engineering,2021,7(5):1787-1807.
[3] 郭一婧,张铭哲,段昶晟,等.无机抗菌材料的抗菌性能研究与应用[J].云南化工,2020,47(9):18-20.
[4] 刘志龙,蒋昊,李美,等.稀土在抗菌材料应用中的研究进展[J].有色金属工程,2022,12(4):20-30.
[5] Nyoka M,Choonara Y E,Kumar P,et al.Synthesis of cerium oxide nanoparticles using various methods:implications for biomedical applications[J].Nanomaterials,2020,10(2):242.
[6] Chatzimentor I,Tsamesidis I,Ioannou M,et al.Study of biological behavior and antimicrobial properties of cerium oxide nanoparticles[J].Pharmaceutics,2023,15(10):2509.
[7] Qi M,Li W,Zheng X,et al.Cerium and its oxidant-based nanomaterials for antibacterial applications:a state-of-the-art review[J].Frontiers in Materials,2020,7:213.
[8] Arunachalam T,Karpagasundaram M,Rajarathinam N.Ultrasound assisted green synthesis of cerium oxide nanoparticles using prosopis juliflora leaf extract and their structural,optical and antibacterial properties[J].Materials Science-Poland,2017,35(4):791-798.
[9] Yefimova S,Klochkov V,Kavok N,et al.Antimicrobial activity and cytotoxicity study of cerium oxide nanoparticles with two different sizes[J].Journal of Biomedical Materials Research Part B:Applied Biomaterials,2023,111(4):872-880.
[10] Balusamy B,Kandhasamy Y G,Senthamizhan A,et al.Cha-racterization and bacterial toxicity of lanthanum oxide bulk and nanoparticles[J].Journal of Rare Earths,2012,30(12):1298-1302.
[11] Negi K,Umar A,Chauhan M S,et al.Ag/CeO2 nanostructured materials for enhanced photocatalytic and antibacterial applications[J].Ceramics International,2019,45(16):20509-20517.
[12] Hannachi E,Khan F A,Slimani Y,et al.Fabrication,characterization,anticancer and antibacterial activities of ZnO nanoparticles doped with Y and Ce elements[J].Journal of Cluster Science,2023,34(4):1777-1788.
[13] Gonca S,Yefimova S,Dizge N,et al.Antimicrobial effects of nanostructured rare-earth-based orthovanadates[J].Current Microbiology,2022,79(9):254.
[14] 徐健,刘丽瑜,梁健,等.银-稀土复合抗菌剂制备及应用研究[J].工业微生物,2023,53(6):45-49.
[15] Munawar T,Mukhtar F,Nadeem M S,et al.Facile synthesis of rare earth metal dual-doped Pr2O3 nanostructures:enhanced electrochemical water-splitting and antimicrobial properties[J].Ceramics International,2022,48(13):19150-19165.
[16] 毛华明,张彬,唐晓宁,等.含稀土铽的载锌抗菌硅胶的制备及协同抗菌机理[J].稀有金属材料与工程,2019,48(8):2667-2676.
[17] Jiang X,Tang X,Zhang B,et al.Antimicrobial activity and synergistic antibacterial mechanism of a combination of zinc and rare-earth scandium against Escherichia coli[J].Materials Technology,2020,35(11/12):797-806.
[18] 洪春水,杨雷,祝文才.稀土掺杂氧化物纳米光催化剂的研究进展[J].广东化工,2024,51(3):81-83.
[19] 陈惠波,叶丽芳,林俊铭,等.稀土掺杂TiO2抗菌薄膜在不锈钢表面上的制备及性能研究[J].化工新型材料,2015,43(9):156-158.
[20] 陈霞,陆改玲,计晶晶,等.稀土元素(镧、铈)掺杂TiO2复合材料的制备及其光催化性和抑菌性的研究[J].人工晶体学报,2020,49(1):62-66.
[21] Ge X,Ren C,Ding Y,et al.Micro/nano-structured TiO2 surface with dual-functional antibacterial effects for biomedical applications[J].Bioact Mater,2019,4:346-357.
[22] Andiappan K,Sanmugam A,Deivanayagam E,et al.Schiff base rare earth metal complexes:studies on functional,optical and thermal properties and assessment of antibacterial activity[J].International Journal of Biological Macromolecules,2019,124:403-410.
[23] Andiappan K,Sanmugam A,Deivanayagam E,et al.Detailed investigations of rare earth (Yb,Er and Pr) based inorganic metal-ion complexes for antibacterial and anticancer applications[J].Inorganic Chemistry Communications,2023,150:110510.
[24] Liu Y,Zhang Q,Zhou N,et al.Study on a novel poly (vinyl alcohol)/graphene oxide-citicoline sodium-lanthanum wound dressing:biocompatibility,bioactivity,antimicrobial activity,and wound healing effect[J].Chemical Engineering Journal,2020,395:125059.
[25] Wang Y,Lu Y,Zhang J,et al.A synergistic antibacterial effect between terbium ions and reduced graphene oxide in a poly(vinyl alcohol)-alginate hydrogel for treating infected chronic wounds[J].Journal of Materials Chemistry B,2019,7(4):538-547.
[26] Xu W,Zhang Z,Zhang X,et al.Peptide hydrogel with antibacterial performance induced by rare earth metal ions[J].Langmuir,2021,37(44):12842-12852.
[27] Zhang M,Zhang C,Zhai X,et al.Antibacterial mechanism and activity of cerium oxide nanoparticles[J].Science China Materials,2019,62(11):1727-1739.
[28] Yefimova S,Klochkov V,Kavok N,et al.Antimicrobial activity and cytotoxicity study of cerium oxide nanoparticles with two different sizes[J].J Biomed Mater Res Part B-Appl Biomater,2023,111(4):872-880.
[29] 刘连升,吴江,张国梁,等.稀土纳米复合材料Ce/Ag/ZnO对白念珠菌的氧化应激抗菌机制研究[J].口腔医学,2021,41(10):878-882.
[30] 姚希燕,唐晓宁,王晓楠,等.无机抗菌材料抗菌机理研究进展[J].材料导报,2021(1):105-111.
[31] Song G,Cheng N,Zhang J,et al.Nanoscale cerium oxide:synthesis,biocatalytic mechanism,and applications[J].Catalysts,2021,11(9):1123.
[32] Jiang M,Zhang B,Tang X,et al.Preparation and characterization of hybrid antimicrobial materials based on Zn-Lu composites[J].Journal of Materials Science,2018,53(21):14922-14932.
[33] Li Y,Fang C,Zhuang W,et al.Antimicrobial enhancement via Cerium(Ⅱ)/Lanthanum(Ⅲ)-doped TiO2 for emergency leak sealing polyurea coating system[J].Npj Materials Degradation,2022,6(1):1-9.
[34] 时代,杨合,薛向欣.Zn、Co单掺杂及Co-Zn共掺杂TiO2纳米材料协同抗菌效应的研究[J].功能材料,2019,50(10):10133-10139.
[35] Świderski G,Gołȩbiewska E,Kowalczyk N,et al.Structure,antioxidant activity and antimicrobial study of light lanthanide complexes with p-coumaric acid[J].Materials,2024,17(6):1324.
[36] Wu L,Yang M,Yao L,et al.Polyaminophosphoric acid-modified ion-imprinted chitosan aerogel with enhanced antimicrobial activity for selective La(Ⅲ) recovery and oil/water separation[J].ACS Applied Materials & Interfaces,2022,14(48):53947-53959.
[37] Liu J,Ren N,Zhang J,et al.Preparation,thermodynamic property and antimicrobial activity of some rare-earth(Ⅲ) complexes with 3-bromo-5-iodobenzoic acid and 1,10-phenanthroline[J].Thermochimica Acta,2013,570:51-58.
[38] Liu G F.Effect of rare earth oxides on properties of nano antibacterial ceramic glaze[J].Key Engineering Materials,2020,852:139-149.
[39] Zambon A,Malavasi G,Pallini A,et al.Cerium containing bioactive glasses:a review[J].ACS Biomater Sci Eng,2021,7(9):4388-4401.
[40] Guo F,Pan F,Zhang W,et al.Robust antibacterial activity of xanthan-gum-stabilized and patterned CeO2-x-TiO2 antifog films[J].ACS Applied Materials & Interfaces,2022,14(39):44158-44172.
[41] Ayon S A,Jamal M,Billah M M,et al.Augmentation of magnetic properties and antimicrobial activities of band gap modified Ho3+ and Sm3+ doped ZnO nanoparticles:a comparative experimental study[J].Journal of Alloys and Compounds,2022,897:163179.
[42] Akioka S,Hirai S,Iijima K,et al.Rare-earth ions as antibacterial agents for woven wool fabric[J].Chemical Papers,2022,76(6):3557-3567.
[43] 张彬,毛华明,唐晓宁,等.稀土-锌抗菌硅胶的制备及在硅橡胶中的应用研究[J].化工新型材料,2019,47(5):231-234.
[44] Li J,Zhu Q,Wu Y,et al.Synthesis,characterization,and applications of rare-earth-based complexes with antibacterial and antialgal properties[J].ACS Applied Bio Materials,2024,7(1):104-113.
基金资助
国家自然科学基金(51965053);内蒙古自然科学基金(2022LHMS05022);内蒙古自治区高校基本科研业务费(242,302);稀土绿色选冶与高质化应用关键技术攻关(YLXKZX-NKD-002)
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