基于多壁碳纳米管(MWCNTs)、石墨烯量子点(GQDs)和纳米金(AuNPs)组成的三维导电网络,并借助量子化学进行分子印迹聚合物设计计算,选取对氨基苯硫酚(p-ATP)和吡咯(Py)作为双功能单体,制备了用于检测组胺的分子印迹电化学传感器。结果表明,三维导电网络的优良导电性以及导电材料与单体之间的强相互作用放大了电化学信号,因而该传感器电导率高,重现性好,对组胺的检测响应良好,线性范围在5~100μmol/L,检出限为0.86μmol/L(信噪比S/N=3)。
This study reported a novel molecularly imprinted polymer network-based electrochemical sensor for detecting histamine based on a three-dimensional conductive network composed of multi-walled carbon nanotubes (MWCNTs),graphene quantum dots (GQDs) and gold nanoparticles (AuNPs),and engineered by quantum chemical computation,utilizing p-aminothiophenol (p-ATP) and pyrrole (Py) as dual functional monomers.The results showed that,the excellent electrical conductivity of the three-dimensional conductive network and the strong interaction between the conductive materials and the monomers (p-ATP) amplified the electrochemical signal.Therefore,the sensor exhibited high conductivity,good reproducibility,and great detection response to histamine.The linear range of the prepared sensor was 5-100μmol/L,and the detection limit was 0.86μmol/L(S/N=3).
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