Progress on preparation and application of nano-sized fluorinated hydroxyapatite

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  • College of Chemical Engineering,Kunming University of Science and Technology, Kunming 650504

Received date: 2021-03-15

  Revised date: 2022-03-24

  Online published: 2022-08-09

Abstract

Fluorine is one of the indispensable elements in human body.Some OH- in hydroxyapatite [HAP,Ca10(PO4)6(OH)2] are replaced by F- to form fluorinated hydroxyapatite [FHA,Ca10(PO4)6(OH)2-xFx].F- replacing the original OH- incorporates into the crystal structure of HAP,which will not change its basic structure,but make HAP more stable and improve the defects of high solubility.Moreover,the growth of bone cells and promote bone union can be stimulated by the F-.The advantages and disadvantages of the preparation methods of nano-FHA and its research progress were introduced,providing a reference for the synthesis of better FHA materials in the future.In addition,the application and development prospect of FHA in biomedical field were also reviewed.

Cite this article

Wang Guoxia, Shan Shaoyun, Zhi Yunfei, Su Hongying, Hu Tianding, Zhang Churu . Progress on preparation and application of nano-sized fluorinated hydroxyapatite[J]. New Chemical Materials, 2022 , 50(7) : 235 -240 . DOI: 10.19817/j.cnki.issn1006-3536.2022.07.048

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