3-Bromopropyl-5,5-dimethylhydantoin was synthesized and grafted on the surface of Fe3O4@SiO2 modified with polyethyleneimine.The quaternarized halamine polymer-functioned Fe3O4@SiO2 nanoparticles were obtained after chlorination.The structure,morphology and characterization of samples were measured by FT-IR,TEM,zeta-potential measurement and VSM.It was super-paramagnetic and could be separated quickly by the aid of an external magnetic field.The results of antibacterial tests showed that the antibacterial mechanism of chlorinated samples was synergistic with quaternary ammonium salt and halamine and the antibacterial property was better than the one without chlorination.100% of S.aureus and E.coli were inactivated within 30min of contact.
[1] 刘国圣.微生物制药及微生物药物分析[J].南方农业,2016,10(3):156-157.
[2] Huang Y F,Wang Y F,Yan X P,et al.Amine-functionalized magnetic nanoparticles for rapid capture and removal of bacterial pathogens[J].Environmental Science & Technology,2010,44(20),7908-7913.
[3] Dong A,Sun Y,Lan S,et al.Barbituric acid-based magnetic n-halamine nanoparticles as recyclable antibacterial agents[J].ACS Appllied Materials & Interfaces,2013,5(16),8125-8133.
[4] Dong A,Wang Y J,Gao G,et al.Chemical insights into antibacterial N-halamines[J].Chemical Review,2017,117(6),4806-4862.
[5] Dong A,Gao G,Chen Y,et al.Modifying Fe3O4-functionalized nanoparticles with N-halamine and their magnetic/antibacterial properties[J].ACS Appllied Materials Interface,2011,3(11),4228-4235.
[6] Haham H,Natan M,Margel S,et al.Engineering of superparamagnetic core-shell iron oxide/N-chloramine nanoparticles for water purification[J].ACS Appllied Materials Interface,2016,8(28),18488-18495.
[7] Shang Y,Xu X,Gao B,et al.Biosorption and bioreduction of perchlorate using the nano Fe3O4-laden quaternary-ammonium chinese reed:considering the coexisting nitrate and nano-Fe3O4[J].ACS Sustainable Chemistry & Engineering,2015,3(9),2220-2231.
[8] 李俊英,李天铎,张庆思等.聚硅氧烷季铵盐的合成及其抗菌性[J].日用化学工业,2004,34(3):154-156.
[9] Li L,Zhao N,Liu S.Versatile surface biofunctionalization of poly(ethylene terephthalate) by interpenetrating polymerization of a butynyl monomer followed by“Click Chemistry”[J].Polymer,2012,53(1):67-78.
[10] 徐光辉,王钰蓉,王文昌等.磁性核壳Fe3O4@SiO2-Ag纳米粒子的制备及性能研究[J].化工新型材料,2016,44(2):49-51,54.
[11] 赵国平,莫尊理,王博等.磁性Fe3O4纳米复合材料的研究进展[J].化工新型材料,2015,43(6):10-13.
[12] Cerkez I,Kocer H B,Worley S D,et al.N-halamine biocidal coatings via a layer-by-layer assembly technique[J].Langmuir,2011,27(7):4091-4907.
基金资助
国家自然科学基金(51603020);吉林省教育厅(JJKH20170555KJ)