主要研究了氧化石墨烯(GO)对阿莫西林(AML)的负载情况。通过超声、振荡、离心和干燥等手段来制备GO-AML复合物,采用傅里叶变换红外光谱和紫外-可见分光光谱等手段对GO-AML复合物进行结构表征。还对不同pH的缓冲溶液中GO对AML的负载情况进行了控释研究。结果表明:GO与阿莫西林以氢键方式结合;在中性条件下负载量大,且在酸性条件下实行效果好。
Graphene oxide (GO) was used to study the loading of amoxicillin (AML).Graphene oxide-amoxicillin (GO-AML) composites were prepared by ultrasonic,vibration,centrifugation and drying.The structure of GO-AML was characterized by FT-IR and UV-Vis.The loading and controlled release of amoxicillin by graphene oxide in different ph buffer solutions were also studied.The results showed that graphene oxide and amoxicillin were combined by hydrogen bonding.Under neutral conditions,the loading was large,and the effect was good under acidic conditions.
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基金资助
山西省自然科学基金(2012021008-4和2014021020-3)
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