采用静电纺丝的方法制得纳米羟基磷灰石(n-HA)/聚乳酸(PLA)(n-HA/PLA)复合纳米纤维支架材料,通过仪器测试,分析研究了不同n-HA用量对n-HA/PLA的形貌与性能的影响。研究结果表明:当n-HA用量为10%(wt,质量分数)条件下,其在聚乳酸纳米纤维表面均匀分布,n-HA/PLA复合纳米纤维支架材料的断裂强度、断裂伸长率达到最大,分别为670.52cN·m/g、105.54%,热性能也得到了提高。
A new kind of n-HA/PLA composite nanofibers’ scaffold material was prepared by electrospinning.The influence of different relative mass fractions of n-HA on the composite’s morphology and properties was researched by using the modern testing tools.The outcomes showed when the relative mass fraction of n-HA in the solution was 10wt%,n-HA particles could disperse into PLA nanofibers evenly and most properties of n-HA/PLA were improved.The break strength was 670.52cN·m/g which was the best of all samples.The elongation at break was 105.54% which was the best,too.The thermal property of n-HA/PLA was also enhanced.
[1] Zhang W J,Chen Zh,Ma S J,et al.Cistanche polysaccharide (CDPS)/polylactic acid (PLA) scaffolds based coaxial electrospinning for vascular tissue engineering[J].International Journal of Polymeric Materials and Polymeric Biomaterials,2016,65(1):38-46.
[2] Zhu X M,Zhong T,Huang R,et al.Preparation of hydrophilic poly(lactic acid) tissue engineering scaffold via (PLA)-(PLA-b-PEG)-(PEG) solution casting and thermal-induced surface structural transformation[J].Journal of Biomaterials Science Polymer Edition,2015,26(17):1286-1296.
[3] Rosenzweig D H,Carelli E,Steffen T,et al.3D-printed ABS and PLA scaffolds for cartilage and nucleus pulposus tissue regeneration[J].International Journal of Molecular Sciences,2015,16(7):15118-15135.
[4] Stefaniab I,Cooper-Whitebcd J J.Development of an in-process UV-crosslinked,electrospun PCL/aPLA-co-TMC composite polymer for tubular tissue engineering applications[J].Acta Biomater,2016,36:231-240.
[5] Andrey S Z,Konstantin L B,Olga B.Gorbatsevitch,synthesis and characterization of organo-inorganic nanoobjects based on hyperbranched polyethoxysiloxanes[J].Silicon,2015,7(2):165-176.
[6] 刘雪莲,扈中武,张胜,等.羟基磷灰石对聚氨酯防火涂料阻燃抑烟性能的影响[J].现代化工,2015,35(5):88-91.
[7] Vimal K,Anshu D,Gupta A P.Studies of poly(lactic acid) based calcium carbonate nanocomposites[J].Composites Part B,Engineering,2014,56(1):184-188.
[8] Chen F M,Liu X H.Advancing biomaterials of human origin for tissue engineering[J].Progress in Polymer Science,2016,53:86-168.
[9] Ajaykumar V,Nupura S B,Marta B,et al.Engineering immu-nomodulatory biomaterials to tune the inflammatory response[J].Trends Biotechnology,2016,36(4):470-482.
[10] 何志贵,陈庆东.非织造材料标准手册[M].北京:中国标准出版社,2009,1-48.
[11] Mir R M,Mehdi R,Farhad S.Investigation of effect of electrospinning parameters on the morphology of polyacrylonitrile/polymethylmethacrylate nanofibers:a box-behnken-based study[J].Journal of Macromolecular Science Part B,Physics,2015,54(8):975-991.
[12] Liao F H,Ju Y Q,Dai X Y,et al.A novel efficient polymeric flame retardant for poly (lactic acid)(PLA):synthesis and its effects on flame retardancy and crystallization of PLA[J].Polymer Degradation and Stability,2015,120:251-261.
[13] Nikpour M R,RabieeS M,Jahanshahi M.Synthesis and characterization of hydroxyapatite/chitosan nanocomposite materials for medical engineering applications[J].Composites Part B Engineering,2012,43(4):1881-1886.
[14] Toshihiro K,Yoshio O,Masayuki N,et al.Preparation and mechanical properties of polylactic acid composites containing hydroxyapatite fibers[J].Biomaterials,2001,22(1):19-23.
基金资助
国家自然科学基金项目(21377004);安徽省高校自然科学研究项目(KJ2015A022,1604b0602024);安徽工程大学校级国家科学基金预研项目(2016yyzr05);安徽省高等学校纺织面料重点实验室开放基金项目(2015FZ005)
PDF
(2314KB)
