To address the issues that silver nanoparticles (AgNPs) are prone to agglomeration leading to decreased antibacterial activity,and free silver ions (Ag+) tend to undergo uncontrolled release causing biological toxicity during application,this study used silver nitrate (AgNO3) as the silver source,glucose (C6H12O6) as the reducing agent,and cellulose nanofibers (CNF) as the carrier to prepare a well-dispersed silver-loaded cellulose nanofiber (CNF-AgNPs) antibacterial composite solution.Subsequently.polyvinylpyrrolidone (PVP) was introduced as a spinning aid,and PVP/CNF-AgNPs antibacterial composite membranes were fabricated via electrospinning.The structure and morphology of CNF-AgNPs and PVP/CNF-AgNPs were analyzed using UV-Vis,XRD,FT-IR,TEM,and SEM.Using the oscillation method with CNF as a control,the antibacterial properties and antibacterial sustained-release performance of the above two materials were investigated.The results demonstrated that when the mass proportion of CNF was 0.25wt% and the concentration of AgNO3 was 2mmol/L,the prepared CNF-AgNPs antibacterial composite solution exhibited excellent dispersibility,and the particle size of AgNPs in the system was smaller.The antibacterial rates of CNF-AgNPs and PVP/CNF-AgNPs against Escherichia coli (E.coli) and Staphylococcus aureus (S.aureus) reached over 99.9%.Moreover,the antibacterial sustained-release effect tests of AgNPs and CNF-AgNPs at three time periods (24h,48h,and 72h) indicated that both materials maintained an antibacterial rate of over 99.9% against E.coli and over 90% against S.aureus.The CNF-AgNPs antibacterial composite system effectively solved the problems of easy agglomeration and easy burst release of AgNPs,providing a safer and more efficient technical solution for the research,development and application of antibacterial functional materials.
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基金资助
2023年“天山英才”培养计划优秀工程师培养项目(2023210390);新疆维吾尔自治区重点研发计划项目(2023B02045-3)
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