水凝胶具有类细胞外基质的内在结构及理化特性,可增强细胞间交流,促进组织再生,在组织工程领域引起了广泛关注,已成为最有潜力的生物活性材料。石墨烯具有独特的导电、导热和力学性能,将石墨烯引入水凝胶基质构建石墨烯基导电水凝胶,大幅拓展了传统水凝胶的应用范围。近年来,石墨烯基导电水凝胶已广泛应用于组织工程、柔性传感器、超级电容器等领域。总结了现阶段石墨烯基导电水凝胶的制备方法及其在皮肤、骨、心肌、神经、骨骼肌修复领域的研究进展,以期为未来组织工程的相关研究提供借鉴。
Hydrogels have the intrinsic structure and physicochemical properties similar to extracellular matrix,which can enhance the communication between cells and promote tissue regeneration.Currently,hydrogels have attracted wide attention in the field of tissue engineering,and have become the most potential bioactive materials.Graphene has unique electrical,thermal and mechanical properties.The introduction of graphene into hydrogel matrix to construct graphene-based conductive hydrogels greatly expands the application range of traditional hydrogels.In recent years,graphene-based conductive hydrogels have been widely used in tissue engineering,flexible sensors,supercapacitors and other fields.In this paper,the preparation methods of graphene-based conductive hydrogels and their research progress in skin,bone,myocardium,nerve and skeletal muscle repair were summarized,aiming to provide a reference for the future research related to tissue engineering.
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基金资助
重庆理工大学研究生教育高质量发展行动计划资助成果(gzlcx20242061);四川大学高等教育教学改革工程(SCU10257)
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