氟硼二吡咯类有机分子因其优异的发光特性成为了近年来研究热点,其已广泛应用在框架材料、生物医学等领域。主要对两种氟硼二吡咯类化合物的合成进行了研究,优化了反应条件。与文献对比,两类分子的合成收率均有大幅提高,分别可达50%和80%以上,并对其结构进行了质谱和核磁氢谱表征。同时对BODIPY分子结构做了衍生化拓展,研究卤化反应及Suzuki偶联反应,丰富了此类分子的种类,拓展了氟硼二吡咯类的应用范围。最后对各类BODIPY分子进行荧光光谱表征。
Boron dipyrromethene (BODIPY) organic molecules have become one of the research hotspots in recent years due to their excellent luminescent properties,and they have been widely used in frame materials,biomedicine and other fields.We mainly studied the synthesis of two types of BODIPY compounds and optimized the reaction conditions.Compared with the literature reports,the synthesis yields of both types of molecules were significantly improved,reaching over 30% and 80%,respectively.Their structures were characterized by mass spectrometry and nuclear magnetic hydrogen spectroscopy.At the same time,the molecular structure of BODIPY was extended by derivatization,and halogenation reactions and Suzuki coupling reactions were investigated,enriching the diversity of such molecules and expanding the application scope of BODIPY.Finally,fluorescence spectra were used to characterize various BODIPY molecules.
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基金资助
国家自然科学基金(21544011)
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