脊髓损伤是一种致残性和破坏性的中枢神经系统损伤,治愈难度大,是临床医学面临的一大难题。三维(3D)生物打印可以制造具有解剖学上精确的复杂几何形状和神经干细胞的空间分布的活神经结构,这在脊髓损伤的治疗中至关重要。介绍了脊髓损伤修复用3D生物打印支架材料的种类、3D生物打印技术的特点以及3D生物打印支架材料的应用情况。
Spinal cord injury is a disabling and destructive injury to the central nervous system,which is difficult to cure and is a major problem faced by clinical medicine.Three-dimensional (3D) bioprinting enables the fabrication of living neural structures with anatomically precise complex geometries and spatial distribution of neural stem cells,which is critical in the treatment of spinal cord injuries.The types of 3D bioprinting scaffold materials for spinal cord injury repair,the characteristics of 3D bioprinting technology and the application of 3D bioprinting scaffold materials were introduced.
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基金资助
安徽省临床医学转化专项(202304295107020012);安徽理工大学医学专项培育项目(YZ2023H2A005)
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