有机硅凝胶具有高透气性,对皮肤友好,无皮肤致敏性,生物相容性好,可消毒、清洗、反复黏贴等优异的性能,是医用硅凝胶的理想材料。巯基-烯点击化学反应是一种高效且环保的光固化技术,具有优异的反应速率和选择性,广泛应用于材料的快速固化过程中。利用巯基-烯点击化学反应制备单组分有机硅凝胶,采用正交试验法,筛选比例,研究不同比例下有机硅凝胶材料的性能。结果表明:当乙烯基硅油黏度为10000cp,巯基硅油2720含量为2.0%,VMQ硅树脂含量为2.0%时,有机硅凝胶综合性能最佳,满足医用有机硅胶粘剂材料的实际使用性能要求。
Silicone gels exhibit high breathability,skin-friendliness,non-skin sensitization,allergy,excellent biocompatibility,and the ability to be sterilized,cleaned and repeatedly adhered,making it an ideal material for medical silicone gels.The thiol-ene click chemistry is an efficient and environmentally friendly photocuring technology with excellent reaction rates and selectivity,and is widely used in the rapid curing process of materials.In this study,single-component silicone gels were prepared using the thiol-ene click chemistry,and an orthogonal experiment was conducted to select the proportion and study the material properties of the silicone gels at different proportions.The results showed that the comprehensive performance of the silicone gel was the best when the viscosity of the vinyl silicone oil was 10000cp,the content of 2720 silicone oil was 2.0% and the content of VMQ resin was 2.0%,meeting the performance requirements for medical silicone gel adhesive materials.
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基金资助
江西省主要学科学术带头人项目(20232BCJ22052);江西省科学院省级财政科研项目(2022YSBG21018);江西省青年基金项目(20242BAB20179);江西省科学院博士项目(2022YYB27和2024YYB30)
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