丝素蛋白水凝胶复合材料结合了丝素蛋白的生物相容性、生物降解性和可调控性,以及水凝胶的高吸水性和渗透性,因此在传感器领域展现出广阔的应用前景。综述了丝素蛋白水凝胶复合材料的制备方法,如物理交联法、化学交联法、酶催化交联法,以及该复合材料在应变传感器、化学传感器和环境传感器等方面的应用进展。基于丝素蛋白水凝胶复合材料的传感器具有灵敏度高、选择性好、性能稳定可靠的特点,有望在医疗诊断、环境监测和生物工程等领域发挥重要作用。
Silk fibroin hydrogel composites integrate the biocompatibility,biodegradability,and tunability of silk fibroin with the high-water absorption and permeability of hydrogels,thereby demonstrating broad application prospects in the field of sensors.This review systematically summarized fabrication strategies for silk fibroin hydrogel composites,including physical crosslinking,chemical crosslinking,and enzyme-catalyzed crosslinking methods,as well as their recent advancements in strain sensors,chemical sensors,and environmental sensors.Sensors based on silk fibroin hydrogel composites exhibited high sensitivity,excellent selectivity,and reliable stability,making them promising candidates for critical roles in medical diagnostics,environmental monitoring,and bioengineering.
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基金资助
河南省自然科学基金(202102210043);河南科技大学大学生创新创业训练计划项目(2023191)
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