抗菌剂在纺织品、木材、水性涂料中均有重要应用。有机和无机材料的共混、接枝通常被认为是组成杀菌体系最有效的方法之一,但是共混物抗菌效果低,时效短,而接枝化学反应可以产生长效抗菌作用。以γ-缩水甘油醚氧丙基三甲氧基硅烷(KH560)作为偶联剂,将聚六亚甲基胍(PHMG)接枝在纳米二氧化铈(CeO2)表面,制备了有机-无机复合型抗菌剂PHMG@CeO2,探究了PHMG对纳米CeO2分散性和粒径大小及分布的影响,以及PHMG分子量对抗菌剂PHMG@CeO2的抗菌性影响。FT-IR、XRD和TGA测试发现,PHMG成功接枝在纳米CeO2表面;SEM、TEM分析发现,PHMG可以有效改善纳米CeO2的分散效果;与CeO2相比,PHMG@CeO2抗菌效果更高。同时,随着PHMG分子量的增加,PHMG@CeO2的抗菌性提升。该复合抗菌体系在聚合物材料中有很好的应用前景。
Antimicrobial agents have important application in textiles,wood,and waterborne coatings.The blending and grafting of organic and inorganic materials are usually considered to be one of the most effective methods to form a sterilization antimicrobial system.However,the blend has low antibacterial effect and short effectiveness,while grafting chemical reaction can produce long-term antibacterial effect.In the paper,an organic-inorganic composite antimicrobial agent PHMG@CeO2 was prepared by grafting PHMG onto the surface of nano-CeO2 using γ-glycidylethoxypropyltrimethoxysilane (KH560) as a coupling agent.The effects of PHMG on the dispersion,particle size and distribution of nano-CeO2,as well as the effects of PHMG molecular weights on antimicrobial properties of HMG@CeO2 were studied.FT-IR,XRD and TGA tests revealed that PHMG was successfully grafted on the surface of nano-CeO2.SEM and TEM tests showed that PHMG could improve the dispersion effect of nano-CeO2 in the aqueous system.Compared with CeO2,PHMG@CeO2 had higher antimicrobial effect.At the same time,the antimicrobial activity of PHMG@CeO2 improved with the increase of molecular weight of PHMG.The composite antimicrobial system has a certain application prospect in polymer materials.
[1] 王则臻,周平,陈朝晖.新型抗菌剂的制备及在亚麻装饰布中的应用[J].印染,2023,49(12):49-53.
[2] Stevenson K B,Gordon S.Policy implications of the society for healthcare epidemiology of America's research plan for reducing healthcare-associated infections[J].Infection Control & Hospital Epidemiology,2010,31(2):124-126.
[3] Odiyo J O,Makungo R.Chemical and microbial quality of groundwater in Siloam village,implications to human health and sources of contamination[J].International Journal of Environmental Research and Public Health,2018,15(2):317.
[4] 陆嘉渔,蔡国强,高宗春,等.纺织品常用的抗菌整理剂的应用综述[J].现代纺织技术,2023,31(3):251-262.
[5] 张跃宇,刘馨忆,许宪祝.新型木材防腐剂的研究进展[J].广州化工,2023,51(15):16-18,22.
[6] 袁豪黎,周逸君,邓书端,等.橡胶木防霉、防腐处理工艺的研究进展[J/OL].林产工业,2024(8):16-20.
[7] 汪腾,王磊,王雅梅.壳聚糖在木材防腐中的应用[J].林产工业,2023,60(7):75-78.
[8] Nistor C L,Mihaescu C I,Bala D,et al.Novel hydrophobic nanostructured antibacterial coatings for metallic surface protection[J].Coatings,2022,12(2):253.
[9] Liu L,Peng W,Zhang X,et al.Rational design of phosphonate/quaternary amine block polymer as an high-efficiency antibacterial coating for metallic substrates[J].Journal of Materials Science & Technology,2021,62(3):96-106.
[10] Deshmukh S P,Koli V B,Dhodamani A G,et al.Ultrasonochemically modified Ag@TiO2 nanocomposites as potent antibacterial agent in the paint formulation for surface disinfection[J].ChemistrySelect,2021,6(1):113-122.
[11] 朱清珂,古菁菁,刘兰奇,等.聚六亚甲基双胍缓释抗菌凝胶的制备和质量评价[J].河南大学学报(医学版),2019,38(3):161-165.
[12] 张艳艳,李欣怡,丁菲宇,等.聚季铵盐抗菌棉织物的制备及抗菌耐洗性能[J].河南工程学院学报(自然科学版),2023,35(1):1-5.
[13] Xue Y,Xiao H,Zhang Y.Antimicrobial polymeric materials with quaternary ammonium and phosphonium salts[J].International Journal of Molecular Sciences,2015,16(2):3626-3655.
[14] Gupta K,Singh R,Pandey A,et al.Photocatalytic antibacterial performance of TiO2 and Ag-doped TiO2 against S.aureus.P.aeruginosa and E.coli[J].Beilstein Journal of Nanotechnology,2013,4(1):345-351.
[15] Wang Y,Wu Y,Yang H,et al.Effect of calcination temperature on the microstructure and antimicrobial activity of boron and cerium co-doped titania nanomaterials[J].Materials Technology,2018,33(1):48-56.
[16] 王小娟.抗菌剂的分类及应用[J].染整技术,2018,40(7):14-17,21.
[17] 徐世欣,姚红蕊,李先亮,等.无机抗菌剂在抗菌涂料中研究进展[J].辽宁化工,2023,52(11):1639-1643.
[18] Maharubin S,Nayak C,Phatak O,et al.Polyvinylchloride coated with silver nanoparticles and zinc oxide nanowires for antimicrobial applications[J].Materials Letters,2019,249(AUG.15):108-111.
[19] 秦广超,张宁坤,汪海晨,等.液相沉淀法制备氧化锌-壳聚糖复合材料及其抗菌性能[J].中国粉体技术,2023,29(1):98-106.
[20] Wang Y,Yu W,Shu A,et al.Polypropylene-grafted poly (hexamethylene guanidine)/modified polyethylene monofilament and its antimicrobial performance[J].International Journal of Polymer Science,2020,2020:1-8.
[21] 谢圣中,胡卓民,黄健,等.碱性水介质中纳米氧化铈的稳定分散研究[J].矿冶工程,2019,39(3):132-135.
[22] 周勇.PHMG的改性及棉织物的抗菌整理研究[D].上海:东华大学,2021.
[23] 谢圣中,胡卓民,黄健,等.碱性水介质中纳米氧化铈的稳定分散研究[J].矿冶工程,2019,39(3):132-135.
基金资助
上海市科技自然基金项目(23ZR1425700)
PDF
