二硫化钼在光动力疗法和光热疗法中的应用

廖师琴, 王清清*

化工新型材料 ›› 2024, Vol. 52 ›› Issue (12) : 263 -269.

PDF
化工新型材料 ›› 2024, Vol. 52 ›› Issue (12) : 263-269. DOI: 10.19817/j.cnki.issn1006-3536.2024.12.050
开发与应用

二硫化钼在光动力疗法和光热疗法中的应用

    廖师琴, 王清清*
作者信息 +

Applications of molybdenum disulfide in photodynamic therapy and photothermal therapy

  • Liao Shiqin, Wang Qingqing
Author information +
文章历史 +
PDF

摘要

综述了MoS2在光动力疗法(PDT)和光热疗法(PTT)中的抗菌应用进展。MoS2凭借其独特的层状结构和高活性位点,成为光驱动抗菌领域的高潜力材料。讨论了PDT与PTT的基本原理及其协同抗菌机制,分析了MoS2的结构特性,展示了MoS2在增强抗菌效果上的优势,并详细阐述了其在PDT、PTT及协同抗菌中的具体应用。然而,当前应用仍面临氧化降解、易聚集、靶向效率低及生物安全性等挑战。未来,需进一步优化MoS2性能,加强安全性评估,以推动其在光驱动抗菌领域的广泛应用。

Abstract

This review summarized the progress in the antibacterial applications of molybdenum disulfide (MoS2) in photodynamic therapy (PDT) and photothermal therapy (PTT).With its unique layered structure and high active sites,MoS2 emerges as a high-potential material in the field of light-driven antibacterial therapy.The paper discussed the fundamental principles of PDT and PTT as well as their synergistic antibacterial mechanisms.The structural properties of MoS2 were analyzed,highlighting its advantages in enhancing antibacterial efficacy.Furthermore,specific applications of MoS2 in PDT,PTT,and their synergistic antibacterial strategies were elaborated.However,current applications still face challenges such as oxidative degradation,easy aggregation,low targeting efficiency,and biosafety concerns.Future research should focus on optimizing the properties of MoS2,strengthening safety assessments,and promoting its widespread application in light-driven antibacterial therapy.

关键词

二硫化钼 / 光动力疗法 / 光热疗法 / 抗菌 / 协同抗菌

Key words

MoS2 / photodynamic therapy / photothermal therapy / antibacterial / synergistic antibacterial

引用本文

引用格式 ▾
二硫化钼在光动力疗法和光热疗法中的应用[J]. 化工新型材料, 2024, 52(12): 263-269 DOI:10.19817/j.cnki.issn1006-3536.2024.12.050

登录浏览全文

4963

注册一个新账户 忘记密码

参考文献

[1] Song L,Sun L,Zhao,J,et al.Synergistic superhydrophobic and photodynamic cotton textiles with remarkable antibacterial activities[J].ACS Applied Bio Materials,2019,2(7):2756-2765.
[2] Alvarado D R,Argyropoulos D S,Scholle F,et al.A facile strategy for photoactive nanocellulose-based antimicrobial materials[J].Green Chemistry,2019,21(12):3424-3435.
[3] Annunzio S R D,Costa N C S,Mezzina R D,et al.Chlorin,phthalocyanine,and porphyrin types derivatives in phototreatment of cutaneous manifestations:a review[J].International Journal of Molecular Sciences,2019,20(16):3861.
[4] 张龙.胆管癌靶向载药纳米囊泡的设计,构建及光热治疗应用研究[D].厦门:厦门大学,2017.
[5] 李黎波,李文敏,项蕾红,等.光动力疗法在中国的应用与临床研究[J].中国激光医学杂志,2012,21(5):278-307.
[6] Cieplik F,Deng D,Crielaard W,et al.Antimicrobial photodynamic therapy-what we know and what we don't[J].Critical Reviews in Microbiology,2018,44(5):571-589.
[7] Carpenter B L,Situ X C,Scholle F,et al.Antiviral,antifungal and antibacterial activities of a bodipy-based photosensitizer[J].Molecules,2015,20(6):10604-10621.
[8] 陈王冰菲.光动力抗菌剂在常见复合纺织材料上的负载及其性能研究[D].无锡:江南大学,2020.
[9] 丁慧颖.光动力治疗基本原理及其应用[M].北京:化学工业出版社,2014.
[10] Jiang L,Gan C R R,Gao J,et al.A perspective on the trends and challenges facing porphyrin-based anti-microbial materials[J].Small,2016,12(27):3609-3644.
[11] Tavares A,Carvalho C M B,Faustino M A,et al.Antimicrobial photodynamic therapy:study of bacterial recovery viability and potential development of resistance after treatment[J].Marine Drugs,2010,8(1):91-105.
[12] Liang Y,Zhao X,Hu T,et al.Adhesive hemostatic conducting injectable composite hydrogels with sustained drug release and photothermal antibacterial activity to promote full-thickness skin regeneration during wound healing[J].Small,2019,15(12):e1900046.
[13] Zhang Y,Zhang S,Zhang Z,et al.Recent progress on NIR-Ⅱ photothermal therapy[J].Frontiers in Chemistry,2021,9(2):728066.
[14] Zhang Y,Lv F,Cheng Y,et al.Pd@Au bimetallic nanoplates decorated mesoporous MnO2 for synergistic nucleus-targeted NIR-Ⅱ photothermal and hypoxia-relieved photodynamic therapy[J].Advanced Healthcare Materials,2020,9(2):1901528.
[15] Li X,Lovell J F,Yoon J,et al.Clinical development and potential of photothermal and photodynamic therapies for cancer[J].Nature Reviews Clinical Oncology,2020,17(11):657-674.
[16] Wang X,Lv F,Li T,et al.Electrospun micropatterned nanocomposites incorporated with Cu2S nanoflowers for skin tumor therapy and wound healing[J].ACS Nano,2017,11(11):11337-11349.
[17] Shi Y,Liu M,Deng F,et al.Recent progress and development on polymeric nanomaterials for photothermal therapy:a brief overview[J].Journal of Materials Chemistry B,2017,5(2):194-206.
[18] Lei W,Ren K,Chen T,et al.Polydopamine nanocoating for effective photothermal killing of bacteria and fungus upon near-infrared irradiation[J].Advanced Materials Interfaces,2016,3(22):1600767.
[19] Nie X,Wu S,Huang F,et al.“Dew-of-Leaf” structure multiple synergetic antimicrobial modality hybrid:a rapid and long lasting bactericidal material[J].Chemical Engineering Journal,2021,416:129072.
[20] Wu Q,Peng R,Luo Y,et al.Antibacterial activity of porous gold nanocomposites via NIR light-triggered photothermal and photodynamic effects[J].ACS Applied Bio Materials,2021,4(6):5071-5079.
[21] Sun J,Song L,Fan Y,et al.Synergistic photodynamic and photothermal antibacterial nanocomposite membrane triggered by single NIR light source[J].ACS Applied Materials & Interfaces,2019,11(30):26581-26589.
[22] Li Y,Liu X,Tan L,et al.Rapid sterilization and accelerated wound healing using Zn2+ and graphene oxide modified g-C3N4 under dual light irradiation[J].Advanced Functional Materials,2018,28(30):1800299.
[23] Wen F,Li P,Meng H,et al.Nitrogen-doped carbon dots/curcumin nanocomposite for combined photodynamic/photothermal dual-mode antibacterial therapy[J].Photodiagnosis and Photodynamics Therapy,2022,39(9):103033.1-103033.8.
[24] Liu B,Su Y,Wu S,et al.Local photothermal/photodynamic synergistic antibacterial therapy based on two-dimensional BP@CQDs triggered by single NIR light source[J].Photodiagnosis and Photodynamic Therapy,2022,39:102905.
[25] Xu M,Hu Y,Xiao L,et al.Near-infrared-controlled nanoplatform exploiting photothermal promotion of peroxidase-like and OXD-like activities for potent antibacterial and anti-biofilm therapies[J].ACS Applied Materials & Interfaces,2020,12(45):50260-50274.
[26] Chu H,Shen J,Wang C,et al.Biodegradable iron-doped ZIF-8 based nanotherapeutic system with synergistic chemodynamic/photothermal/chemo-therapy[J].Colloids and Surfaces A:Physicochemical and Engineering Aspects,2021,628,127388.
[27] Rajasekar S,Santhi K,Farheena M I,et al.Polydopamine coated molybdenum disulfide nanoflower as an efficient material for synergistic chemo-photothermal therapy[J].Journal of Cluster Science,2023,34(6):2931-2940.
[28] 赵月华.二硫化钼纳米材料的制备及其催化性能的应用研究[D].北京:中国科学院大学,2019.
[29] 周青伟.二硫化钼及其复合材料的制备与性能研究[D].南京:南京大学,2019.
[30] Li D,Xiong W,Jiang L,et al.Multimodal nonlinear optical imaging of MoS2 and MoS2-based Van Der Waals heterostructures[J].ACS Nano,2016,10(3):3766-3775.
[31] 张家豪,王德修,李玉琦,等.二硫化钼纳米材料的制备方法及应用研究进展[J].人工晶体学报,2024,53(4):600-619.
[32] Zhao J,Zhang P,Fan J,et al.Constructing 2D layered MoS2 nanosheets-modified Z-scheme TiO2/WO3 nanofibers ternary nanojunction with enhanced photocatalytic activity[J].Applied Surface Science,2018,430:466-474.
[33] Wang Z,Mi B.Environmental applications of 2D molybdenum disulfide (MoS2) nanosheets[J].Environmental Science and Technology,2017,51(15):8229-8244.
[34] Bang G S,Cho S,Son N,et al.DNA-assisted exfoliation of tungsten dichalcogenides and their antibacterial effect[J].ACS Applied Materials & Interfaces,2016,8(3):1943-1950.
[35] Kim T I,Kwon B,Yoon J,et al.Antibacterial activities of graphene oxide molybdenum disulfide nanocomposite films[J].ACS Applied Materials & Interfaces,2017,9(9):7908-7917.
[36] Appel J H,Li D O,Podlevsky J D,et al.Low cytotoxicity and genotoxicity of two-dimensional MoS2 and WS2[J].ACS Biomaterials Science and Engineering,2016,2(3):361-367.
[37] Wang X,Mansukhani N D,Guiney L M,et al.Differences in the toxicological potential of 2D versus aggregated molybdenum disulfide in the lung[J].Small,2015,11(38):5079-5087.
[38] Tian X,Sun Y,Fan S,et al.Photogenerated charge carriers in molybdenum disulfide quantum dots with enhanced antibacterial activity[J].ACS Applied Materials and Interfaces,2019,11(5):4858-4866.
[39] 刘成.二硫化钼基复合材料的合成及其光催化性能研究[D].西安:西北大学,2019.
[40] Parzinger E,Miller B,Blaschke B,et al.Photocatalytic stability of single- and few-layer MoS2[J].ACS Nano,2015,9(11):11302-11309.
[41] Wang J,Yan M,Zhao K,et al.Field effect enhanced hydrogen evolution reaction of MoS2 nanosheets[J].Advanced Materials,2017,29(7):1604464.
[42] Dong H,Tang S,Hao Y,et al.Fluorescent MoS2 quantum dots:ultrasonic preparation,up-conversion and down-conversion bioimaging,and photodynamic therapy[J].ACS Applied Materials and Interfaces,2016,8(5):3107-3114.
[43] Cao W,Yue L,and Wang Z.High antibacterial activity of chitosan-molybdenum disulfide nanocomposite[J].Carbohydrate Polymers,2019,215:226-234.
[44] Zhang W,Kuang Z,Song P,et al.Synthesis of a two-dimensional molybdenum disulfide nanosheet and ultrasensitive trapping of staphylococcus aureus for enhanced photothermal and antibacterial wound-healing therapy[J].Nanomaterials,2022,12(11):1865.
[45] Yin W,Yu J,Lv F,et al.Functionalized nano-MoS2 with peroxidase catalytic and near-infrared photothermal activities for safe and synergetic wound antibacterial applications[J].ACS Nano,2016,10(12):11000-11011.
[46] Liu B,Li C,Chen G,et al.Synthesis and optimization of MoS2@Fe3O4-ICG/Pt(Ⅳ) nanoflowers for MR/IR/PA bioimaging and combined PTT/PDT/chemotherapy triggered by 808nm laser[J].Advanced Science,2017,4(8):1600540.
[47] Feng Z,Liu X,Tan L,et al.Electrophoretic deposited stable chitosan@MoS2 coating with rapid in situ bacteria-killing ability under dual-light irradiation[J].Small,2018,14(21):e1704347.
[48] Li G,Meng F,Lu T,et al.Functionalised molybdenum disulfide nanosheets for co-delivery of doxorubicin and siRNA for combined chemo/gene/photothermal therapy on multidrug-resistant cancer[J].Journal of Pharmacy and Pharmacology,2021,73(8):1128-1135.
[49] Qi Y,Yuan Y,Qian Z,et al.Injectable and self-healing polysaccharide hydrogel loading molybdenum disulfide nanoflakes for synergistic photothermal-photodynamic therapy of breast cancer[J].Macromolecular Bioscience,2022,22(9):e2200161.
[50] Murugan C,Park S.Cerium ferrite@molybdenum disulfide nanozyme for intracellular ROS generation and photothermal-based cancer therapy[J].Journal of Photochemistry and Photobiology A:Chemistry,2023,437:114466.
[51] Chen H,Zhao X,Cui B,et al.Peroxidase-like MoS2/Ag nanosheets with synergistically enhanced NIR-responsive antibacterial activities[J].Frontiers in Chemistry,2023,11:1148354.
[52] Nurdiwijayanto L,Ma R,Sakai N,et al.Insight into the structural and electronic nature of chemically exfoliated molybdenum disulfide nanosheets in aqueous dispersions[J].Dalton Transactions,2018,47(9):3014-3021.
[53] Wang H,Wang N,Wang F,et al.Spherical montmorillonite-supported molybdenum disulfide nanosheets as a self-sedimentary catalyst for organic pollutants removal[J].Separation and Purification Technology,2020(251):117346.
[54] Zhou Z,Li X,Hu T,et al.Molybdenum-based nanomaterials for photothermal cancer therapy[J].Advanced NanoBiomed Research,2022,2(11):2200065.
[55] 沈慧颖.细菌纤维素-二硫化钼基材料的制备及其光敏性能研究[D].无锡:江南大学,2022.
[56] 金伟豪.生物被膜微环境响应的二硫化钼纳米载体及光疗协同抗耐药菌和促伤口愈合研究[D].合肥:安徽工程大学,2023.

基金资助

江西省教育厅科学技术研究项目(GJJ212406和GJJ202405)

AI Summary AI Mindmap
PDF

478

访问

0

被引

导航
相关文章

AI思维导图

/