丝素蛋白(SF)具有优良的生物相容性、生物可降解性,在生物医学领域有着广泛的应用。纳晶纤维素(NCC)来源于纤维素,具有高强度、大比表面积的优良性能,应用在复合材料、生物医药等多个领域。以SF为基材,NCC作增强剂,纳米Ag作抗菌剂,制备了一种具有抗菌性能和一定机械强度的SF/NCC载Ag共混膜。对所制备膜的形貌、结构、力学性能、抗菌性能等进行表征与分析。结果表明,SF/NCC载Ag纳米纤维膜具良好的机械强度和一定的抗菌性能,在医疗和包装材料等方面具有潜在的应用价值。
Silk fibroin (SF) has excellent biocompatibility and biodegradability,and is widely used in the field of biomedicine.Nanocrystalline cellulose (NCC) is derived from cellulose and has excellent properties of high strength and large specific surface area.It is applied in many fields such as composite materials and biomedicine.In this paper,a SF/NCC-supported silver blend membrane with antibacterial properties and certain mechanical strength was prepared by using SF as substrate,NCC as reinforcement agent and nano-Ag as antibacterial agent.The morphology,structure,mechanical properties and antibacterial properties of the prepared membranes were characterized and analyzed.The results showed that the prepared SF/NCC-supported silver membrane had good mechanical strength and certain antibacterial properties,holding potential applications in medical treatment and packaging materials.
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基金资助
国家自然科学基金(21706093)
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