环境响应纳米纤维是可以感知外界刺激变化并自身发生物理化学性能改变的智能材料。纳米纤维具有直径小、孔隙率大、比表面积高的优点,因此环境响应纳米纤维有更高的响应灵敏度,更快的响应速率,成为近年来的研究热点。综述了温度、pH、光、磁场等类型环境响应纳米纤维的研究现状,归纳了环境响应纳米纤维的制备方法和近几年的主要应用,如药物控释、传感器及分离纯化等领域,并对其研究前景进行了展望。
Environmental response nanofibers are intelligent materials that can sense external stimulation change and undergo physical and chemical property alterations.Nanofibers have the advantages of small diameter,large porosity,and high specific surface area,so the environmental response nanofibers have higher response sensitivity and faster response rate,making them have become a hot research topic in recent years.In this paper,the research status of the environmental response nanofibers for temperature,pH,light and magnetic field was reviewed,the preparation methods of environmental response nanofibers and their main applications in recent years,such as drug controlled release,sensors,separation and purification,were summarized,and the research prospect was also discussed.
[1] Chen R,Lin L L,Wang H Y,et al.Effects of morphologies of thermosensitive electrospun nanofibers on controllable drug release[J].Tissue Engineering Part A,2021,27(11-12):724-732.
[2] Liu L,Bai S Q,Yang H Q,et al.Controlled release from thermo-sensitive PNVCL-co-MAA electrospun nanofibers:the effects of hydrophilicity/hydrophobicity of a drug[J].Materials Science & Engineering C-Materials for Biological Applications,2016,67:581-589.
[3] Zhang R Y,Zaslavski E,Vasilyev G,et al.Tunable pH-responsive chitosan-poly(acrylic acid) electrospun fibers[J].Biomacromolecules,2018,19(2):588-595.
[4] Zhang C D,Wu S H,Qin X H.Facile fabrication of novel pH-sensitive poly(aspartic acid) hydrogel by crosslinking nanofibers[J].Materials Letters,2014,132:393-396.
[5] Dong Y S,Lu X W,Wang P X,et al.Facile fabrication of a “Catch and Release” cellulose acetate nanofiber interface:a platform for reversible glycoprotein capture and bacterial attachment[J].Journal of Materials Chemistry B,2018,6(42):6744-6751.
[6] Street S T G,He Y X,Harniman R L,et al.Precision polymer nanofibers with a responsive polyelectrolyte corona designed as a modular,functionalizable nanomedicine platform[J].Polymer Chemistry,2022,13(20):3009-3025.
[7] Schoeller J,Itel F,Wuertz-Kozak K,et al.pH-responsive chitosan/alginate polyelectrolyte complexes on electrospun PLGA nanofibers for controlled drug release[J].Nanomaterials,2021,11(7):1850.
[8] 雷颖,葛冲冲,冯瑾,等.pH响应型三维纳米纤维的构建及其性能研究[J].材料导报,2021,35(z2):508-512.
[9] Lam K Y,Lee C S,Pichika M R,et al.Light-responsive polyurethanes:classification of light-responsive moieties,light-responsive reactions,and their applications[J].RSC Advances,2022,12(24):15261-15283.
[10] Chen M L,Nielsen S R,Uyar T,et al.Electrospun UV-responsive supramolecular nanofibers from a cyclodextrin-azobenzene inclusion complex[J].Journal of Materials Chemistry C,2013,1(4):850-855.
[11] Azimi R,Abdollahi A,Roghani-Mamaqani H,et al.Dual-mode security anticounterfeiting and encoding by electrospinning of highly photoluminescent spiropyran nanofibers[J].Journal of Materials Chemistry C,2021,9(30):9571-9583.
[12] Jia Y F,Yang C Y,Chen X Y,et al.A review on electrospun magnetic nanomaterials:methods,properties and applications[J].Journal of Materials Chemistry C,2021,9(29):9042-9082.
[13] 杨旭东,胡阳,胡吉永,等.PCL/Fe3O4磁性复合纳米纤维的结构与性能[J].化工新型材料,2016,44(11):178-180.
[14] Guarino V,Ausanio G,Iannotti V,et al.Electrospun nanofiber tubes with elastomagnetic properties for biomedical use[J].Express Polymer Letters,2018,12(4):318-329.
[15] Wang B L,Zheng H X,Chang M W,et al.Hollow polycaprolactone composite fibers for controlled magnetic responsive antifungal drug release[J].Colloids and Surfaces B-Biointerfaces,2016,145:757-767.
[16] Du L,Quan X,Fan X F,et al.Electro-responsive carbon membranes with reversible superhydrophobicity/superhydrophilicity switch for efficient oil/water separation[J].Separation and Purification Technology,2019,210:891-899.
[17] Che H L,Huo M,Peng L,et al.CO2-responsive nanofibrous membranes with switchable oil/water wettability[J].Angewandte Chemie-International Edition,2015,54(31):8934-8938.
[18] Kim Y J,Ebara M,Aoyagi T.A smart hyperthermia nanofiber with switchable drug release for inducing cancer apoptosis[J].Advanced Functional Materials,2013,23(46):5753-5761.
[19] Gorji M,Zarbaf D,Mazinani S,et al.Multi-responsive on-demand drug delivery PMMA-co-PDEAEMA platform based on CO2,electric potential,and pH switchable nanofibrous membranes[J].Journal of Biomaterials Science-Polymer Edition,2023,34(3):351-371.
[20] Wang X F,Ding B,Sun G,et al.Electro-spinning/netting:a strategy for the fabrication of three-dimensional polymer nano-fiber/nets[J].Progress in Materials Science,2013,58(8):1173-1243.
[21] Li C G,Qiu Y H,Li R G,et al.Preparation of poly (N-isopropylacrylamide)/polycaprolactone electrospun nanofibres as thermoresponsive drug delivery systems in wound dressing[J].International Journal of Polymeric Materials and Polymeric Biomaterials,2023,72(3):243-251.
[22] Lin X L,Tang D Y,Lyu H T,et al.Poly(N-isopropylacrylamide)/polyurethane core-sheath nanofibres by coaxial electrospinning for drug controlled release[J].Micro & Nano Letters,2016,11(5):260-263.
[23] Gleason K K.Controlled release utilizing initiated chemical vapor deposited (iCVD) of polymeric nanolayers[J].Frontiers in Bioengineering and Biotechnology,2021,9:632753.
[24] Sayin S,Tufani A,Emanet M,et al.Electrospun nanofibers with pH-responsive coatings for control of release kinetics[J].Frontiers in Bioengineering and Biotechnology,2019,7:309.
[25] Sanchez L D,Brack N,Postma A,et al.Surface modification of electrospun fibres for biomedical applications:a focus on radical polymerization methods[J].Biomaterials,2016,106:24-45.
[26] Tiwari A P,Bhattarai D P,Maharjan B,et al.Polydopamine-based implantable multifunctional nanocarpet for highly efficient photothermalchemo therapy[J].Scientific Reports,2019,9(1):1-13.
[27] Ma W J,Samal S K,Liu Z C,et al.Dual pH- and ammonia-vapor-responsive electrospun nanofibrous membranes for oil-water separations[J].Journal of Membrane Science,2017,537:128-139.
[28] Kamsani N H,Haris M S,Pandey M,et al.Biomedical application of responsive ‘smart’ electrospun nanofibers in drug delivery system:a minireview[J].Arabian Journal of Chemistry,2021,14(7):103199.
[29] Li H Y,Liu K L,Williams G R,et al.Dual temperature and pH responsive nanofiber formulations prepared by electrospinning[J].Colloids and Surfaces B-Biointerfaces,2018,171:142-149.
[30] Guo H W,Tan S J,Gao J,et al.Sequential release of drugs form a dual-delivery system based on pH-responsive nanofibrous mats towards wound care[J].Journal of Materials Chemistry B,2020,8(8):1759-1770.
[31] 梁渝廷.温度、pH双重响应性智能纳米纤维的制备及其药物缓释性能研究[D].南宁:广西大学,2020.
[32] Liang F C,Kuo C C,Chen B Y,et al.RGB-switchable porous electrospun nanofiber chemoprobe-filter prepared from multifunctional copolymers for versatile sensing of ph and heavy metals[J].ACS Applied Materials & Interfaces,2017,9(19):16381-16396.
[33] Wu W C,Lai H J.Preparation of thermo-responsive electrospun nanofibers containing rhodamine-based fluorescent sensor for Cu2+ detection[J].Journal of Polymer Research,2016,23(11):1-11.
[34] Liang F C,Luo Y L,Kuo C C,et al.Novel magnet and thermoresponsive chemosensory electrospinning fluorescent nanofibers and their sensing capability for metal ions[J].Polymers,2017,9(4):136.
[35] 杨春宇,陈思浩,楼建中,等.静电纺纳米复合纤维在气体传感器中的应用研究进展[J].化工新型材料,2016,44(6):13-15.
[36] Chen B Y,Lung Y C,Kuo C C,et al.Novel multifunctional luminescent electrospun fluorescent nanofiber chemosensor-filters and their versatile sensing of pH,temperature,and metal ions[J].Polymers,2018,10(11):1259.
[37] Yeh C T,Chen C Y.pH-responsive and pyrene based electrospun nanofibers for DNA adsorption and detection[J].RSC Advances,2017,7(10):6023-6030.
[38] Chen L N,Chiu Y C,Hung J J,et al.Multifunctional electrospun nanofi bers prepared from poly((N-isopropylacrylamide) co-(N-hydroxymethylacrylamide)) and their blends with 1,2-diaminoanthraquinone for NO gas detection[J].Macromolecular Chemistry and Physics,2014,215(3):286-294.
[39] Lin S J,Shang J J,Theato P.Facile fabrication of CO2-responsive nanofibers from photo-cross-linked poly(pentafluorophenyl acrylate) nanofibers[J].ACS Macro Letters,2018,7(4):431-436.
[40] Li J J,Zhou Y N,Jiang Z D,et al.Electrospun fibrous mat with pH-switchable superwettability that can separate layered oil/water mixtures[J].Langmuir,2016,32(50):13358-13366.
[41] Wei B B,Wang K,Wang J R,et al.Thermo-modulated nanofibrous skin covered janus membranes forefficient oil/water separation[J].Colloids and Surfaces a-Physicochemical and Engineering Aspects,2022,641:127935.
[42] Thakur N,Ranganath A S,Sopiha K,et al.Thermoresponsive cellulose acetate-poly(N-isopropylacrylamide) core-shell fibers for controlled capture and release of moisture[J].ACS Applied Materials & Interfaces,2017,9(34):29224-29233.
[43] Lin K Y A,Lin J T,Lu X Y,et al.Electrospun magnetic cobalt-embedded carbon nanofiber as a heterogeneous catalyst for activation of oxone for degradation of Amaranth dye[J].Journal of Colloid and Interface Science,2017,505:728-735.
[44] Liu L,Jiang S H,Sun Y,et al.Giving direction to motion and surface with ultra-fast speed using oriented hydrogel fibers[J].Advanced Functional Materials,2016,26(7):1021-1027.
[45] Kim S,Choi H.Switchable wettability of thermoresponsive core-shell nanofibers for water capture and release[J].ACS Sustainable Chemistry & Engineering,2019,7(24):19870-19879.
[46] Jia S Y,Tan J V,Tan J,et al.Stimuli-responsive swollen electrospun fiber catalyst for efficient degradation of organic pollutants[J].Journal of Environmental Chemical Engineering,2022,10(5):108366.
[47] Shao D Y,Song W J,Qin X H,et al.A precisely designed composite actuator with directionally fast actuation,non-contact operation,and obstacle-penetrating triggering ability using aligned nanofibers and alternating magnetic field[J].Macromolecular Materials and Engineering,2022,307(9):2200219.
基金资助
国家自然科学基金资助(52070142)
PDF
