以苯并异噻唑啉酮(BIT)、N-甲基烯丙基胺和三光气为原料,设计合成N-烯丙基-N-甲基取代的苯并异噻唑啉-3-酮甲酰胺单体;然后与甲基丙烯酸甲脂、丙烯酸丁酯等进行共聚反应,得到BIT功能化的丙烯酸树脂共聚物。活性测试结果表明,该类树脂对藻类及菌类的生长均有明显抑制作用。抑藻性能测试发现,共聚物对球等鞭金藻的抑制作用最强,对蛋白核小球藻最弱。抑菌性能测试发现,共聚物对金黄色葡萄球菌的抑制作用最强,对副溶血性弧菌最弱。
Monomer N-allyl-N-methyl substituted benzisothiazolin-3-one carboxamide was designed and synthetised with BIT,N-allylmethylamine and triphosgene as raw materials,and the monomer was combined with n-butyl acrylate and methyl methacrylate for the synthesis of BIT functionalized acrylic resin copolymer.The structures of the copolymer were identified by means of IR and 1H-NMR,and determined the bioactivities.the results of the algal inhibition shown that the resin had obvious inhibitory effect on the growth of algae and bacteria,the inhibition effect of Isochrysis galbana was the strongest,and Chlorella pyrenoidosa was the weakest.As to antibacterial activities test,the copolymer had the strongest inhibitory effect on Staphylococcus aureus,the Vibrio Parahemolyticus was the weakest.
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