综述与专论

超滤膜在医用领域的研究进展

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  • 中石化(北京)化工研究院有限公司,北京 100013
赵慕华(1992-),女,博士,研究方向为吸附分离材料,E-mail:zhaomh.bjhy@sinopec.com。
刘轶群,教授,博士研究生导师,研究方向为聚合物分离膜材料,E-mail:liuyq.bjhy@sinopec.com。

收稿日期: 2024-02-01

  修回日期: 2024-10-18

  网络出版日期: 2025-03-19

Research progress of ultrafiltration membrane in medical field

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  • SINOPEC Beijing Research Institute of Chemical Industry,Beijing 100013

Received date: 2024-02-01

  Revised date: 2024-10-18

  Online published: 2025-03-19

摘要

随着人口老龄化的加剧和社会对生命健康的关注,超滤膜在医用领域的需求日益增长,近年来,超滤膜在生物、医用制品领域的研究取得了诸多进展。详细总结了超滤膜在血液透析过滤、除病毒过滤、中药分离领域的研究进展,重点梳理了相关膜的结构特点和要求,对比分析了超滤膜在不同应用场景下重点关注的技术效果。基于此,可以认为,超滤膜膜孔结构的调控、降低溶出以及提高膜抗污性能是超滤膜在医用领域的重要发展方向。亲水改性是提高膜抗污染性能的主要技术手段,但与此同时引入的亲水性聚合物洗脱是溶出物的主要来源。将亲水聚合物交联或接枝共聚是解决溶出问题的关键。

本文引用格式

赵慕华, 张建华, 吕静兰, 奚振宇, 潘国元, 刘轶群 . 超滤膜在医用领域的研究进展[J]. 化工新型材料, 2025 , 53(3) : 65 -71 . DOI: 10.19817/j.cnki.issn1006-3536.2025.03.041

Abstract

With the intensification of population aging and social concern for life and health,the demand for ultrafiltration membranes in the medical field is increasing.In recent years,research on ultrafiltration membranes in the fields of biology and medical products has made substantial progress.This article provided a detailed summary of the research progress of ultrafiltration membranes in the fields of blood dialysis filtration,virus removal filtration,and traditional Chinese medicine separation.It highlighted the structural characteristics and requirements of relevant membranes,and conducted a comparative analyse of the key technical effects of ultrafiltration membranes in different application scenarios.Based on this,it could be assumed that regulating the pore structure of ultrafiltration membranes,reducing dissolution,and improving membrane fouling resistance were important development directions for ultrafiltration membranes in the medical field.Hydrophilic modification was the main technical means to improve the anti-fouling performance of membranes,but at the same time,the introduction of hydrophilic polymer elution was the main source of dissolved substances.Cross linking or grafting copolymerization of hydrophilic polymers was the key for addressing the leaching issue.

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