化工新型材料

化工新型材料 ›› 2017, Vol. 45 ›› Issue (9) : 20-22.

综述与专论

超临界CO₂中合成医用生物可降解高分子材料的研究进展

^1,2

^1,2*

作者信息 +

Research progress of biomedical degradable material synthesized in supercritical CO₂

Wang Jingchang^1,2, Yuan Haoqi^1,2, Wang Wenhuan^1,2, Hou Weimin^1,2, Zhan Shiping^1,2

Author information +

文章历史 +

Received		Published
2016-04-07		2017-10-19
Issue Date	Revised Date
2017-10-19	2016-04-07

PDF

摘要

介绍了超临界CO₂的特性,概述了常用可降解医用生物高分子材料的研究进展。介绍了超临界CO₂中合成可降解医用生物高分子材料的研究进展,探讨了超临界中可降解生物医用材料合成中存在的问题及研究发展方向。

Abstract

The characteristics of supercritical CO₂ were described,an overview of commonly linear aliphatic biomedical degradable polymer material was introduced and the advances was described at home and aboard in this field.Finally,the problems of material synthesis were discussed and the tendency of the research development was forecasted.

关键词

超临界CO₂ / 生物医用材料 / 可降解

Key words

supercritical CO₂ / biomedical medical material / degradable property

引用本文

引用格式 ▾

超临界CO₂中合成医用生物可降解高分子材料的研究进展[J]. 化工新型材料, 2017, 45(9): 20-22 DOI:

登录浏览全文

4963

注册一个新账户忘记密码

参考文献

原文顺序 | 出版日期 | 本文引用

[1] 闫玉华.生物可降解医用材料的研究进展[J].骨科材料与临床研究,2005,2(2):39-42.
[2] 张庆富,杨文芳.超临界CO₂的应用技术及发展现状[J].毛纺科技,2011,39(8):48-54.
[3] 郑岚,陈开勋.超临界CO₂技术的应用和发展新动向[J].石油化工,2012,41(5):501-509.
[4] 王冉.浅谈功能高分子材料[J].农家科技(下旬刊),2013,3(4):148-149.
[5] 袁团.利用CO₂制备脲类化合物的研究[D].太原:中北大学,2014.
[6] 王勇.可生物降解两亲性聚天冬氨酸衍生物的合成及其pH敏感性研究[D].天津:南开大学,2009.
[7] Yeo S D,Kiran E.Formation of polymer particles with supercritical fluids:a review[J].J Supercrit Fluids,2005,34(3):287-308.
[8] 魏天飞.生物可降解材料成为发展趋势[J].中国包装工业,2011(6):30-30.
[9] 罗时荷,汪朝阳,杨丽庭,等.直接法共聚改性聚乳酸研究新进展[J].高分子通报,2011(1):7-15.
[10] 郭超.聚乳酸多孔支架的制备和性能研究[D].南京:东南大学,2007.
[11] 祖恩峰.L-丙交酯的合成、表征及共聚[D].西安:西北工业大学,2006.
[12] 陈蕾.羟基磷灰石/聚己内酯/聚乳酸复合材料的制备与研究[D].合肥:安徽大学,2008.
[13] 黄星,任建鹏,詹世平.超临界CO₂中合成PCL及其共聚物的研究进展[J].化工新型材料,2012,40(4):28-30.
[14] 於秋霞.聚己内酯合成与改性的研究[D].西安:西北工业大学,2010.
[15] 詹传明.长循环靶向载丝裂霉素壳聚糖纳米粒的制备和药效学研究[D].厦门:厦门大学,2011.
[16] 李华.PLCL的制备及DEX/PLCL芯/壳超细纤维研究[D].天津:天津大学,2008.
[17] 徐艳.纺织结构生物复合材料人工气管的研制[D].上海:东华大学,2008.
[18] Visseher G E,Robin R L.Biodegradation of an tissue reaction to 50:50 Poly(D,L-lactide-co-glycolide) microcapsules[J].Jounal of Biomedical Materials Research,1985,19(3):349-365.
[19] Hile D,Pishko M V.Ring-opening precipiation ploymerization of Poly(D,L-lactide-co-glycolide)in supercritical carbon dioxide[J].Macromol Rapid Commun,1999,20(10):511-514.
[20] Hile D,Pishko M V.Emulsion coploymerization of D,L-lactide and glycolide in supercritical carbon dioxide[J].Journal of Polymer Science,Part A:Pulymer Chemistry,2001,39(4):562-570.
[21] Bratton D,Brown M,Howdle S M.Tin(Ⅱ) ethyl hexanoate catalyzed precipitation polymerization of ε-caprolactone in supercritical carbon dioxide[J].Macromolecules,2005,38(4):1190-1195.
[22] 陈爱政,康永强,王士斌,等.超临界流体技术构建壳聚糖纳米粒/PLLA-PEG-PLLA复合微粒及其表征[J].化工学报,2015,66(4):1565-1576.
[23] Campardelli R,Oleandro E,Revechon E.Supercritical assisted injection in a liquid antisolvent for PLGA and PLA microparticle production[J].Powder Technology,2015,287:12-19.
[24] 张赪.超临界流体技术制备PLLA-PEG载5-FU纳米微粒的研究[D].上海:复旦大学,2011.
[25] Thurecht S,Loeker F C,Duxbury C J,et al.Enzyme catalyzed ring-opening polymerization of ε-caprolactone in supercritical carbon dioxide[J].Macromolecules,2004,37(7):2450-2453.
[26] Kang Y,Wu JG,Huang Z,et al.Preparation,characterization and in vitro cytotoxicity of indomethacin-loaded PLLA/PLGA microparticles using supercritical CO₂ technique[J].European Journal of Pharmaceutics and Biopharmaceutics,2008,70:85-87.