Preparation and its antibacterial and sustained release properties of Ag-bio-MOF
Xu Guangnian, Ruan Guolian, Zhu Jiguang, Jin Juncheng
Technology Promotion Center of Nano Composite Material Preparation and Application,Anhui Provincial Laboratory of Biomimetic Sensor and Detecting Technology,West Anhui University,Lu'an 237012
Abstract: The silver loaded coordination polymer (Ag-bio-MOF) was synthesized by chemical reduction using the synthetic [Cd3(dpa)(DMF)2(H2O)3]·DMF (bio-MOF) as the carrier and AgNO3 as precursor,then the structure of composite prepared were characterized by X-ray single crystal diffraction (XRSCD) and X-ray diffraction (XRD).The silver ions content loaded on composite was about 3.3wt% determined by Volhard method,and its sustained release property was determined by immersion of deionized water repeatedly.The minimum inhibition concentration (MIC) of the composite was 50μg/mL and the sterilizing efficiency (SE) was over 99% against Escherichia coli ATCC 11229(E.coli).Moreover,the SE of supernatant to Escherichia coli was still more than 99% although after 5 times consecutive soaking by deionized water,indicating that Ag particles in/on the Ag-bio-MOF had an excellent sustained release performance.
徐光年, 阮果连, 朱继广, 金俊成. 载银配合物的制备及其抗菌与缓释性能研究[J]. 化工新型材料, 2019, 47(11): 171-174.
Xu Guangnian, Ruan Guolian, Zhu Jiguang, Jin Juncheng. Preparation and its antibacterial and sustained release properties of Ag-bio-MOF. New Chemical Materials, 2019, 47(11): 171-174.
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